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While evidence of myocarditis can be found in all patients with <jats:styled-content style=\"fixed-case\">KD<\/jats:styled-content> on histology specimens, only a minority of patients are clinically symptomatic. Occasionally children can present with <jats:styled-content style=\"fixed-case\">KD<\/jats:styled-content> shock syndrome and hemodynamic instability as a result of decreased systolic function and vasoplegia. Several children with <jats:styled-content style=\"fixed-case\">KD<\/jats:styled-content> have depressed shortening fraction on echocardiography. Increased end\u2010systolic and end\u2010diastolic dimensions, strain abnormalities and diastolic dysfunction are also found in a significant proportion of patients. Echocardiographic signs of myocarditis improve after the acute phase and do so more quickly in patients who have received intravenous immunoglobulins, as opposed to those given only aspirin. Normalization of systolic function is typically observed over long\u2010term follow\u2010up; however, more subtle abnormalities (strain, diastolic function) may persist. It is noteworthy that myocarditis associated with <jats:styled-content style=\"fixed-case\">KD<\/jats:styled-content> can occur in absence of coronary artery abnormalities. <jats:styled-content style=\"fixed-case\">KD<\/jats:styled-content> myocarditis can result in long\u2010term sequelae.<\/jats:p>","DOI":"10.1111\/1756-185x.13219","type":"journal-article","created":{"date-parts":[[2017,11,3]],"date-time":"2017-11-03T14:59:17Z","timestamp":1509721157000},"page":"45-49","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":82,"title":["Myocarditis and Kawasaki disease"],"prefix":"10.1111","volume":"21","author":[{"given":"Audrey","family":"Dionne","sequence":"first","affiliation":[{"name":"Department of Cardiology Boston Children's Hospital Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagib","family":"Dahdah","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology CHU 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