{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T07:35:19Z","timestamp":1780472119111,"version":"3.54.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T00:00:00Z","timestamp":1515110400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the frequency and risk factors of asymptomatic vertebral fractures in inflammatory myositis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>Dorsal and lumbar spine lateral radiographs were taken for adults with inflammatory myositis and scored using Genant's semi\u2010quantitative technique. Demographic data, weight, height, postmenopausal status, duration of corticosteroid use, drug intake, co\u2010morbidities and past history of fractures were recorded. Bone mineral density (<jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content>) was assessed using dual\u2010energy X\u2010ray absorptiometry (<jats:styled-content style=\"fixed-case\">DEXA<\/jats:styled-content>). Myositis Damage Index (<jats:styled-content style=\"fixed-case\">MDI<\/jats:styled-content>) was also assessed. All results are expressed in median and interquartile range.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred patients (82 female) with myositis of median age 35.5 (28.5\u201346) years and disease duration 3.0 (1.81\u20138.0) years were studied. Thirty\u2010five patients had adult dermatomyositis (<jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>), 26 polymyositis, 31 connective tissue disease\u2010associated myositis and eight had juvenile onset myositis. Seventeen were postmenopausal women. Forty\u2010six patients had asymptomatic vertebral fractures and 19 had more than one fracture. Half the fractures occurred in those with disease duration of &lt;5\u00a0years. Of the 69 fractures, 47 (68.1%), 16 (23.2%) and 6 (8.7%) were mild, moderate and severe, respectively. The 11th and 12th thoracic vertebrae were together the most commonly (30.4%) affected. Of the 70 who underwent <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content> assessment, 62.7% were osteopenic and 26.9% were osteoporotic. T scores of <jats:styled-content style=\"fixed-case\">DEXA<\/jats:styled-content> scan at the lower third of the radius correlated negatively with fracture number (<jats:italic>r\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>\u22120.27 (\u22120.50 to \u22120.005), <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.04). Gender, age, disease duration, years of corticosteroid intake, body mass index, years post\u2010menopause and <jats:styled-content style=\"fixed-case\">MDI<\/jats:styled-content> had no correlation with number of fractures.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with inflammatory myositis have high prevalence of asymptomatic vertebral fractures.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13257","type":"journal-article","created":{"date-parts":[[2018,1,9]],"date-time":"2018-01-09T21:59:44Z","timestamp":1515535184000},"page":"725-731","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Prevalence and predictors of asymptomatic vertebral fractures in inflammatory myositis"],"prefix":"10.1111","volume":"21","author":[{"given":"Latika","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Clinical Immunology and Rheumatology Sanjay Gandhi Postgraduate 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