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Gout is not a new disease, which was first documented nearly 5,000 years ago. The prevalence of gout has increased globally in recent years, imposing great disease burden worldwide. Moreover, gout or hyperuricemia is clearly associated with a variety of comorbidities, including cardiovascular diseases, chronic kidney disease, urolithiasis, metabolic syndrome, diabetes mellitus, thyroid dysfunction, and psoriasis. To prevent acute arthritis attacks and complications, earlier use of pharmacotherapeutic treatment should be considered, and patients with hyperuricemia and previous episodes of acute gouty arthritis should receive long\u2010term urate\u2010lowering treatment. Urate\u2010lowering drugs should be used during the inter\u2010critical and chronic stages to prevent recurrent gout attacks, which may elicit gradual resolution of tophi. The goal of urate\u2010lowering therapy should aim to maintain serum uric acid (sUA) level &lt;6.0 mg\/dL. For patients with tophi, the initial goal can be set at lowering sUA to &lt;5.0 mg\/dL to promote tophi dissolution. The goal of this consensus paper was to improve gout and hyperuricemia management at a more comprehensive level. The content of this consensus paper was developed based on local epidemiology and current clinical practice, as well as consensuses from two multidisciplinary meetings and recommendations from Taiwan Guideline for the Management of Gout and Hyperuricemia.<\/jats:p>","DOI":"10.1111\/1756-185x.13266","type":"journal-article","created":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T04:06:49Z","timestamp":1516766809000},"page":"772-787","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":136,"title":["Management of gout and hyperuricemia: Multidisciplinary consensus in Taiwan"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6251-0231","authenticated-orcid":false,"given":"Kuang\u2010Hui","family":"Yu","sequence":"first","affiliation":[{"name":"Division of Rheumatology, Allergy, and Immunology Chang Gung Memorial Hospital Chang Gung University Taipei 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