{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T19:12:42Z","timestamp":1780600362349,"version":"3.54.1"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2018,7,2]],"date-time":"2018-07-02T00:00:00Z","timestamp":1530489600000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","award":["2015R1D1A1A01057559"],"award-info":[{"award-number":["2015R1D1A1A01057559"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control & Prevention","doi-asserted-by":"publisher","award":["2001\u2013347\u20136111\u2013221"],"award-info":[{"award-number":["2001\u2013347\u20136111\u2013221"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control & Prevention","doi-asserted-by":"publisher","award":["2002\u2013347\u20136111\u2013221"],"award-info":[{"award-number":["2002\u2013347\u20136111\u2013221"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control & Prevention","doi-asserted-by":"publisher","award":["2003\u2013347\u20136111\u2013221"],"award-info":[{"award-number":["2003\u2013347\u20136111\u2013221"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control & Prevention","doi-asserted-by":"publisher","award":["2004\u2010E71001\u201300"],"award-info":[{"award-number":["2004\u2010E71001\u201300"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control & Prevention","doi-asserted-by":"publisher","award":["2005\u2010E71001\u201300"],"award-info":[{"award-number":["2005\u2010E71001\u201300"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control & Prevention","doi-asserted-by":"publisher","award":["2006\u2010E71006\u201300"],"award-info":[{"award-number":["2006\u2010E71006\u201300"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control & Prevention","doi-asserted-by":"publisher","award":["2013\u2010E71007\u201300"],"award-info":[{"award-number":["2013\u2010E71007\u201300"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003669","name":"Korea Centers for Disease Control & Prevention","doi-asserted-by":"publisher","award":["2014\u2010E71005\u201300"],"award-info":[{"award-number":["2014\u2010E71005\u201300"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Chondrocalcinosis results from deposition of calcium pyrophosphate dihydrate in articular cartilage. It is a relatively common radiographic finding of the joints, especially the knee. This study investigated the incidence and the risk factors for the development of knee chondrocalcinosis in the general population.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We used a prospective, ongoing cohort, composed of 5018 people, which was established in 2001 to investigate the epidemiologic characteristics of major chronic diseases in the Republic of Korea. The incidence of knee chondrocalcinosis was assessed per 1000 person\u2010years, and the risk factors were explored by Cox proportional hazard regression analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 4543 patients who did not have knee chondrocalcinosis at enrollment, year 2001\u20132002, were evaluated with a mean follow\u2010up duration of 8.4\u00a0\u00b1\u00a04.2\u00a0years. The crude incidence of knee chondrocalcinosis was 3.19 per 1000 person\u2010years (women, 3.55; men, 2.70), and the whole cumulative incidence of knee chondrocalcinosis was 2.7%. Older age (&gt;\u00a055\u00a0years) and higher HbA1C were associated with increased risk of knee chondrocalcinosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This is the first study to report the incidence of knee chondrocalcinosis in the general population of Korea. Older age and high HbA1C were independent risk factors for development of knee chondrocalcinosis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13317","type":"journal-article","created":{"date-parts":[[2018,7,3]],"date-time":"2018-07-03T06:17:26Z","timestamp":1530598646000},"page":"1391-1397","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Incidence of knee chondrocalcinosis and its risk factors in a community\u2010based cohort"],"prefix":"10.1111","volume":"21","author":[{"given":"Nam H.","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Preventive Medicine Ajou University School of Medicine Suwon Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoonah","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Radiology SmileBon Hospital Pyeongtaek Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seunghun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology Hanyang University Hospital for Rheumatic Diseases Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoon\u2010Kyoung","family":"Sung","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Hanyang University Hospital for Rheumatic Diseases Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0208-0505","authenticated-orcid":false,"given":"Jae\u2010Bum","family":"Jun","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Hanyang University Hospital for Rheumatic Diseases Seoul Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,7,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.139105"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2014.01.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2006.08.001"},{"key":"e_1_2_7_5_1","first-page":"2","article-title":"Ultrasound imaging for the rheumatologist. XXV. Sonographic assessment of the knee in patients with gout and calcium pyrophosphate deposition disease","volume":"28","author":"Filippucci E","year":"2010","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.161057"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kes204"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.22189"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2014.04.022"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2013.08.003"},{"key":"e_1_2_7_11_1","unstructured":"Annual Anseong(official description of Ansung in English)Statistics Report(https:\/\/www.anseong.go.kr\/ Registered No. 71\u20134080000\u2013000001\u201310). April 2016."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2011.150508"},{"key":"e_1_2_7_13_1","first-page":"981","article-title":"Prevalence of chondrocalcinosis in Italian subjects from northeastern Italy. The Pro.V.A. (PROgetto Veneto Anziani) study","volume":"27","author":"Ramonda R","year":"2009","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2017-097503"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-014-2797-6"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/03009742.2012.713983"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2014.01.005"},{"key":"e_1_2_7_18_1","first-page":"569","article-title":"Calcium pyrophosphate dihydrate crystal deposition: a clinical and laboratory analysis of 91 Thai patients","volume":"82","author":"Louthrenoo W","year":"1999","journal-title":"J Med Assoc Thai"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573399810602040455"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar4043"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1756-185X.13317","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.13317","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T04:34:07Z","timestamp":1695011647000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1756-185X.13317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":19,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1111\/1756-185X.13317"],"URL":"https:\/\/doi.org\/10.1111\/1756-185x.13317","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"value":"1756-1841","type":"print"},{"value":"1756-185X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"2018-07-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}