{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T06:55:19Z","timestamp":1751525719349,"version":"3.37.3"},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,10,21]],"date-time":"2018-10-21T00:00:00Z","timestamp":1540080000000},"content-version":"vor","delay-in-days":50,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100010425","name":"Tri-Service General Hospital","doi-asserted-by":"publisher","award":["TSGH\u2010C107\u2010004"],"award-info":[{"award-number":["TSGH\u2010C107\u2010004"]}],"id":[{"id":"10.13039\/501100010425","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The pathophysiology of adhesive capsulitis (<jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>) is uncertain. We noted patients with gout seemed to have higher incidence rates of <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> than other people in our clinic. We did not know the true relationship between gout and <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> because there are no published reports so far. The aim of this study is to verify the risk of developing <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> following gout exposure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>The authors used the National Health Insurance Research Database of Taiwan to select 39\u00a0094 subjects with newly diagnosed gout and randomly extracted 78\u00a0188 matched control subjects. All of the subjects in study and control groups were followed until the event of <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>. Cox proportional hazard regression analyses were performed to evaluate the subsequent risk of <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was significance since the 8th year of tracking that patients with gout had a higher risk for <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> (log\u2010rank test <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>.001). Cox regression showed the adjusted hazard ratio of developing <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> for patients with gout was 1.71 (95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> = 1.451\u20102.565, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>.001) than the control group. Stratified analysis showed that gout patients have a higher risk for <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content> regardless of diabetes mellitus, stroke or carotid artery disease (<jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study showed that gout is an independent risk factor for developing <jats:styled-content style=\"fixed-case\">AC<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13347","type":"journal-article","created":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T00:25:53Z","timestamp":1540167953000},"page":"1716-1722","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Increased risk of adhesive capsulitis among patients with gout: A nationwide population\u2010based matched\u2010cohort study"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5884-6872","authenticated-orcid":false,"given":"Kao\u2010Chih","family":"Hsu","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Tri\u2010Service General Hospital School of Medicine National Defense Medical Center Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia\u2010Hung","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Tri\u2010Service General Hospital Song\u2010Shan Branch National Defense Medical Center Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yin\u2010Yin","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Tri\u2010Service General Hospital School of Medicine National Defense Medical Center Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang\u2010Cheng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Tri\u2010Service General Hospital School of Medicine National Defense Medical Center Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yung\u2010Tsan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Tri\u2010Service General Hospital School of Medicine National Defense Medical Center Taipei Taiwan"},{"name":"Integrated Pain Management Center Tri\u2010Service General Hospital School of Medicine National Defense Medical Center Taipei Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu\u2010Chien","family":"Chien","sequence":"additional","affiliation":[{"name":"School of Public Health National Defense Medical Center Taipei Taiwan"},{"name":"Department of Medical Research 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