{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T21:31:03Z","timestamp":1761514263034,"version":"3.37.3"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T00:00:00Z","timestamp":1536105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>A new sonoelastography technique \u2013 virtual touch tissue quantification of acoustic radiation force impulses (<jats:styled-content style=\"fixed-case\">ARFI<\/jats:styled-content>) \u2013 offers a promising method for measuring tissue rigidity. The aim of this study was to assess the usefulness of <jats:styled-content style=\"fixed-case\">ARFI<\/jats:styled-content> for diagnosing Sj\u00f6gren's syndrome (<jats:styled-content style=\"fixed-case\">SS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This transversal prospective study included 41 patients with <jats:styled-content style=\"fixed-case\">SS<\/jats:styled-content> according to American\u2010European Consensus Group (<jats:styled-content style=\"fixed-case\">AECG<\/jats:styled-content>) criteria, and a control group without symptoms. All subjects underwent <jats:styled-content style=\"fixed-case\">ARFI<\/jats:styled-content> high\u2010resolution ultrasound assessment of the parotid glands (<jats:styled-content style=\"fixed-case\">PG<\/jats:styled-content>) and submandibular glands (<jats:styled-content style=\"fixed-case\">SMG<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In patients with <jats:styled-content style=\"fixed-case\">SS<\/jats:styled-content>, parotid gland shear wave velocity (<jats:styled-content style=\"fixed-case\">SWV<\/jats:styled-content>) was 2.08\u00a0m\/s\u00a0\u00b1\u00a00.55, significantly higher than in control subjects (1.2\u00a0m\/s\u00a0\u00b1\u00a00.17) (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.0001); submandibular gland <jats:styled-content style=\"fixed-case\">SWV<\/jats:styled-content> was higher in <jats:styled-content style=\"fixed-case\">SS<\/jats:styled-content> patients (2.12\u00a0m\/s\u00a0\u00b1\u00a00.44) than control subjects (1.56\u00a0m\/s\u00a0\u00b1\u00a00.16) (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Acoustic radiation force impulses sonoelastography can assist diagnosis of <jats:styled-content style=\"fixed-case\">SS<\/jats:styled-content>, and is a non\u2010invasive and fast method of detecting pathological changes to the parotid and submandibular glands.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13373","type":"journal-article","created":{"date-parts":[[2018,9,6]],"date-time":"2018-09-06T03:23:48Z","timestamp":1536204228000},"page":"175-181","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Is sonoelastography a helpful method of evaluation to diagnose Sj\u00f6gren's 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