{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:58:15Z","timestamp":1740149895272,"version":"3.37.3"},"reference-count":36,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,10,18]],"date-time":"2018-10-18T00:00:00Z","timestamp":1539820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007225","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["MOST 106\u20102314\u2010B\u2010037\u2010034","MOST 107\u20102314\u2010B\u2010037\u2010088"],"award-info":[{"award-number":["MOST 106\u20102314\u2010B\u2010037\u2010034","MOST 107\u20102314\u2010B\u2010037\u2010088"]}],"id":[{"id":"10.13039\/100007225","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004694","name":"Kaohsiung Medical University","doi-asserted-by":"publisher","award":["KMU\u2010M106006","KMU\u2010M106032"],"award-info":[{"award-number":["KMU\u2010M106006","KMU\u2010M106032"]}],"id":[{"id":"10.13039\/501100004694","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Gout is a common complication in kidney transplant recipients. This study evaluated the association between kidney transplant recipients and the long\u2010term risk of incident gout.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>For this age\u2010matched and sex\u2010matched retrospective cohort study, the Catastrophic Illness Certificate Database and the National Health Insurance Research Database were combined between 1997 and 2010. The study included 5917 patients with kidney transplants and 23 668 matched kidney transplant\u2010free subjects. Hazard ratio (<jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>) for risk of incident gout was calculated using the Cox proportional hazards regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In this study, of the 5917 kidney transplant recipients, 521 (8.8%) had gout. The kidney transplant group had a higher risk of incident gout than those in the matched kidney transplant\u2010free group (adjusted <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> = 1.55, 95% confidence intervals [<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>] = 1.36\u20101.77), particularly within 3 years following kidney transplant recipients (adjusted <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> = 2.61, 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> = 2.13\u20103.20). We observed that at the &gt;3 to 6 years and the &gt;6 to 9 years follow\u2010up, patients with kidney transplant did not have a significant association with risk of incident gout (adjusted <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> = 0.92, <jats:italic>P<\/jats:italic> = 0.4806 and adjusted <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content> = 1.26, <jats:italic>P<\/jats:italic> = 0.1901, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These findings revealed that risk of incident gout increased within 3 years following kidney transplant recipients and the individual's long\u2010term risk of incident gout between kidney transplant recipients and the general population remained similar.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13393","type":"journal-article","created":{"date-parts":[[2018,10,19]],"date-time":"2018-10-19T02:50:28Z","timestamp":1539917428000},"page":"1993-2001","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Risk of incident gout in kidney transplant recipients: A retrospective cohort study"],"prefix":"10.1111","volume":"21","author":[{"given":"Fransiska Romana","family":"Simbolon","sequence":"first","affiliation":[{"name":"Graduate Institute of Medicine College of Medicine Kaohsiung Medical University Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su\u2010Shin","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery Department of Surgery Kaohsiung Medical University Hospital Kaohsiung Taiwan"},{"name":"Department of Surgery Faculty of Medicine College of Medicine Kaohsiung Medical University 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