{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T05:49:29Z","timestamp":1794116969072,"version":"4.8.0"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,4,26]],"date-time":"2019-04-26T00:00:00Z","timestamp":1556236800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the point prevalence of depression and anxiety in psoriatic arthritis and putative reductions in these comorbidities with the treatment of psoriatic arthritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We performed a systematic review in accordance with PRISMA guidelines examining point prevalence of depression and anxiety in psoriatic arthritis as well as effects of treatment for psoriatic arthritis on these psychiatric comorbidities. MEDLINE, EMBASE, EBM Reviews and Cochrane, and PsycINFO were searched from inception to October 2017. Quality of studies was assessed using the Joanna Briggs Institute Checklist for Prevalence Studies. Study and population characteristics were extracted and entered into an electronic database for subsequent descriptive and meta\u2010analysis of point prevalence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Result<\/jats:title><jats:p>Three studies matched inclusion criteria with significant statistical heterogeneity. The prevalence of depression ranged between 9%\u201022% and anxiety between 15%\u201030% in patients with psoriatic arthritis. One study matched inclusion criteria for treatment effect analysis, albeit with a high risk of bias and illustrated a benefit of etanercept on the prevalence of depression (9% vs 16%) and anxiety (14% vs 30%) after 24\u00a0weeks of treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This is the first systematic review of point prevalence of depression and anxiety in patients with psoriatic arthritis. There is a moderate point prevalence of both depression and anxiety in patients with psoriatic arthritis, which is similar or slightly higher than the general population and comparable to that seen in other rheumatic diseases. The effects of treatment for psoriatic arthritis on comorbid depression and anxiety remain unclear.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13553","type":"journal-article","created":{"date-parts":[[2019,4,26]],"date-time":"2019-04-26T11:33:35Z","timestamp":1556278415000},"page":"967-973","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["Systematic review of depression and anxiety in psoriatic arthritis"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6006-903X","authenticated-orcid":false,"given":"Narainraj","family":"Kamalaraj","sequence":"first","affiliation":[{"name":"Campbelltown Hospital Sydney New South Wales Australia"},{"name":"University of Edinburgh Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"El\u2010Haddad","sequence":"additional","affiliation":[{"name":"Campbelltown Hospital Sydney New South Wales Australia"},{"name":"Western Sydney University Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillipa","family":"Hay","sequence":"additional","affiliation":[{"name":"Western Sydney University Sydney New South Wales Australia"},{"name":"Translational Health Research Institute Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Pile","sequence":"additional","affiliation":[{"name":"Campbelltown Hospital Sydney New South Wales Australia"},{"name":"Western Sydney University Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,26]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-244X-12-6"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2016.112"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-017-1234-1"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13891"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2011.01.100121"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1017\/S003329171200147X"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200104)45:2<151::AID-ANR168>3.0.CO;2-T"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-211284"},{"issue":"10","key":"e_1_2_6_10_1","first-page":"894","article-title":"Analysis of the hospital anxiety and depression scale in psoriatic arthritis: results from the presta study","volume":"67","author":"Ndosi M","year":"2015","journal-title":"Arthritis Rheumatol"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2009.06.005"},{"issue":"2","key":"e_1_2_6_12_1","first-page":"ii3\u20108","article-title":"Classification and diagnostic criteria for psoriatic arthritis","volume":"64","author":"Helliwell PS","year":"2005","journal-title":"Ann Rheum Dis"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_6_14_1","unstructured":"World Health Organization.The ICD\u201010 classification of mental and behavioural disorders: diagnostic criteria for research Geneva World Health Organization 1993;http:\/\/www.who.int\/iris\/handle\/10665\/37108. 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