{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T02:43:34Z","timestamp":1779245014304,"version":"3.51.4"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T00:00:00Z","timestamp":1555286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>We aimed to evaluate subclinical atherosclerosis based on carotid intima\u2010media thickness (CIMT) and arterial stiffness measurements in patients with Beh\u00e7et's disease (BD), using ultrasound (US) radiofrequency (RF) data technology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included 33 BD patients and 33 healthy controls in this study. The participants did not have any primary cardiovascular risk factors, such as diabetes mellitus, hypertension, hyperlipidemia and obesity. All participants were evaluated using Doppler ultrasonography. Arterial stiffness and CIMT measurements were performed in bilateral common carotid arteries using the US RF data technology.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The right, left and mean CIMT values were similar between the patient and control groups (<jats:italic>P<\/jats:italic> &gt;\u00a00.05). There was also no statistically significant difference in the right side <jats:italic>\u03b1<\/jats:italic> and <jats:italic>\u03b2<\/jats:italic> stiffness indices despite higher values in the patient group (P\u00a0&gt; 0.05). The right, left and mean distensibility coefficient (DC) and compliance coefficient (CC) values of the patient group were significantly lower than the control group (<jats:italic>P<\/jats:italic>\u00a0&lt; 0.05). The left and mean <jats:italic>\u03b1<\/jats:italic>\u2010 and <jats:italic>\u03b2<\/jats:italic>\u2010stiffness indices, and the right, left and mean pulse wave velocity (PWV) values were significantly higher in the patient group (<jats:italic>P<\/jats:italic>\u00a0&lt; 0.05). We found higher mean CIMT and PWV values, and <jats:italic>\u03b1<\/jats:italic>\u2010 and <jats:italic>\u03b2<\/jats:italic>\u2010stiffness indices in patients with mucocutaneous involvement compared with those with major organ involvement, while the mean DC and CC values were lower in the former. However, these results did not reach a statistically significant level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrated evidence of subclinical atherosclerosis in BD in the absence of major atherosclerotic risk factors.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13579","type":"journal-article","created":{"date-parts":[[2019,4,15]],"date-time":"2019-04-15T11:04:29Z","timestamp":1555326269000},"page":"781-788","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Evaluation of subclinical atherosclerosis by ultrasound radiofrequency data technology in patients with Beh\u00e7et's disease"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7475-3927","authenticated-orcid":false,"given":"Cem","family":"Ozisler","sequence":"first","affiliation":[{"name":"Department of Rheumatology, Diskapi Yildirim Beyazit Training and Research Hospital University of Health Sciences Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatice","family":"Kaplanoglu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital University of Health Sciences Ankara Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,4,15]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2017.12.006"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2018.3"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18102034"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2012.06.023"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01058"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.5551\/jat.31989"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.21037\/qims.2016.05.03"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.2174\/1874192401004010083"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2018.00064"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2012.05.014"},{"key":"e_1_2_5_12_1","first-page":"121","article-title":"Evaluation of subclinical atherosclerosis in migraine patients by ultrasound radiofrequency datatechnology: preliminary results","volume":"28","author":"G\u00fcne\u015f Tatar \u0130","year":"2016","journal-title":"Agri"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2013.32.1.105"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2015.112"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2007.09.009"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-200301000-00006"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13324"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.5606\/tjr.2012.016"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2011.08.006"},{"issue":"8697","key":"e_1_2_5_20_1","first-page":"1078","article-title":"Criteria for diagnosis of Beh\u00e7et's disease. 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