{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T20:41:27Z","timestamp":1773348087972,"version":"3.50.1"},"reference-count":52,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T00:00:00Z","timestamp":1557100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81472130, 81672225, 81601941, 81501923"],"award-info":[{"award-number":["81472130, 81672225, 81601941, 81501923"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010021","name":"Postdoctoral Science Foundation of Central South University","doi-asserted-by":"publisher","award":["182130"],"award-info":[{"award-number":["182130"]}],"id":[{"id":"10.13039\/501100010021","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To systematically examine the existing literature on the associations between chondrocalcinosis (CC) and osteoarthritis (OA) at different joints, and to quantify such associations through meta\u2010analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>PubMed, Embase and Scopus databases were searched through from inception to June 2017. Cohort, case\u2010control or cross\u2010sectional studies were included if they examined the association between CC and OA. Data on the odds ratios (OR) and their 95% confidence intervals (CI) of the prevalence or progression of OA between the CC group and non\u2010CC group with respect to the same joint were extracted.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 14 studies were identified. Twelve studies were eligible for assessing the association between knee CC and knee OA. The combined data showed a positive association between them (OR\u00a0=\u00a02.84; 95% CI, 2.12\u20103.81; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001). Three studies were eligible for assessing the association between hip CC and hip OA. The data on the OR could only be extracted from one study (OR\u00a0=\u00a00.92; 95% CI, 0.68\u20101.24; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.59). Two studies were eligible for assessing the association between hand CC and hand OA, and the data on the OR could only be extracted from one study which reported significant associations between CC and OA at the metacarpophalangeal joint (OR\u00a0=\u00a04.75; 95% CI, 2.12\u201010.64; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001) and the wrist joint (OR\u00a0=\u00a04.44; 95% CI, 3.56\u20105.54; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study established a strong association between knee CC and knee OA. However, the associations between CC and OA at the hip or hand still remain controversial and warrant further study.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13583","type":"journal-article","created":{"date-parts":[[2019,5,6]],"date-time":"2019-05-06T21:23:44Z","timestamp":1557177824000},"page":"1175-1182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Association between chondrocalcinosis and osteoarthritis: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"22","author":[{"given":"Yilun","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Wei","sequence":"additional","affiliation":[{"name":"Health Management Center, Xiangya Hospital Central South University Changsha Hunan China"},{"name":"Department of Epidemiology and Health Statistics, Xiangya School of Public Health Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongxing","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuo","family":"Yang","sequence":"additional","affiliation":[{"name":"Health Management Center, Xiangya Hospital Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Ding","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Cui","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yilin","family":"Xiong","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiatian","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2987-138X","authenticated-orcid":false,"given":"Guanghua","family":"Lei","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Xiangya Hospital Central South University Changsha Hunan China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,5,6]]},"reference":[{"issue":"9","key":"e_1_2_8_2_1","first-page":"1241","article-title":"The prevalence of chondrocalcinosis in the elderly and its association with knee osteoarthritis: the Framingham Study","volume":"16","author":"Felson DT","year":"1989","journal-title":"J Rheumatol"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2003.015206"},{"issue":"6","key":"e_1_2_8_4_1","first-page":"981","article-title":"Prevalence of chondrocalcinosis in Italian subjects from northeastern Italy. 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