{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T01:45:24Z","timestamp":1793411124320,"version":"4.5.0"},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T00:00:00Z","timestamp":1569801600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Antineutrophil cytoplasmic antibody (ANCA)\u2010associated vasculitis (AAV) and immunoglobulin G4\u2010related disease (IgG4\u2010RD) have some common features. The co\u2010occurrence\/concurrence of AAV and IgG4\u2010RD was recently published by the collaborative European Vasculitis Study Group. First, we aimed to investigate ANCA positivity of our IgG4\u2010RD cohort. Second, a literature review of co\u2010occurrence\/concurrence of AAV and IgG4\u2010RD was done.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data of 62 patients with IgG4\u2010RD in Hacettepe Vasculitis Center Database were used. Patient dataset was designed to include demographic data, clinical characteristics, imaging and IgG4\u2010RD, AAV and ANCA test results. At the next step, we performed a systematic literature review in PUBMED database covering the time period from 1976 until April 2018. Relevant publications were searched using these MeSH terms \u2018\u2018IgG4\u2010related disease and Anti\u2010Neutrophil Cytoplasmic Antibody\u2010Associated Vasculitis\u2019\u2019, \u201cIgG4\u2010related disease and Eosinophilic Granulomatosis with Polyangiitis\u201d, \u201cIgG4\u2010related disease and Microscopic Polyangiitis\u201d and \u201cIgG4\u2010related disease and Granulomatosis with Polyangiitis\u201d.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three (10.3%) of 29 patients had low titer ANCA positivity. These three patients didn't have any findings of vasculitis and no granuloma was seen in biopsy. In the literature review, we found 17 cases had features of both IgG4\u2010RD and AAV. These cases were re\u2010evaluated according to the Comprehensive Diagnostic Criteria for IgG4\u2010RD. ANCA were positive in 15 of 17 patients (88%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>None of our IgG4\u2010RD patients overlapped with AAV. Only two patients in the literature review seemed to be fully compatible with both diseases. Even though AAV and IgG4\u2010RD share similar clinical features, we think this might be a co\u2010occurrence instead of a histopathological link.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13693","type":"journal-article","created":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T06:14:35Z","timestamp":1569910475000},"page":"1926-1932","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Do ANCA\u2010associated vasculitides and IgG4\u2010related disease really overlap or not?"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8084-2018","authenticated-orcid":false,"given":"Abdulsamet","family":"Erden","sequence":"first","affiliation":[{"name":"Division of Rheumatology Department of Internal Medicine Faculty of Medicine Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3886-2813","authenticated-orcid":false,"given":"Ertugrul Cagri","family":"Bolek","sequence":"additional","affiliation":[{"name":"Division of Rheumatology Department of Internal Medicine Faculty of Medicine Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kubra Gozde","family":"Yardimci","sequence":"additional","affiliation":[{"name":"Division of Rheumatology Department of Internal Medicine Faculty of Medicine Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levent","family":"Kilic","sequence":"additional","affiliation":[{"name":"Division of Rheumatology Department of Internal Medicine Faculty of Medicine Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sule Apras","family":"Bilgen","sequence":"additional","affiliation":[{"name":"Division of Rheumatology Department of Internal Medicine Faculty of Medicine Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omer","family":"Karadag","sequence":"additional","affiliation":[{"name":"Division of Rheumatology Department of Internal Medicine Faculty of Medicine Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,9,30]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3906\/sag-1704-150"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-016-3195-z"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.37715"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2017.07.020"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-011-0571-z"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2012.72"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.40375"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(66)90214-2"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2011.155382"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/121702"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.1991.tb05647.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcx134"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2013.05.023"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2014.12.020"},{"issue":"5","key":"e_1_2_6_16_1","doi-asserted-by":"crossref","first-page":"780","DOI":"10.3109\/14397595.2014.915510","article-title":"A case of ANCA\u2010negative renal small\u2010vessel vasculitis with tubulointerstitial infiltration of IgG4\u2010positive plasma cells","volume":"26","author":"Sakairi T","year":"2016","journal-title":"Mod Rheumatol"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-012-0613-1"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2017.01.001"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000004633"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.51.7725"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.51.6074"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000006707"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2015.11.021"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2017.07.012"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000341"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0003489415625072"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/1066896917754252"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.51.6599"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.14712\/18059694.2015.74"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.3109\/09273948.2012.709574"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1756-185X.13693","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.13693","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1756-185X.13693","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.13693","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T08:40:14Z","timestamp":1694248814000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1756-185X.13693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,30]]},"references-count":29,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1111\/1756-185X.13693"],"URL":"https:\/\/doi.org\/10.1111\/1756-185x.13693","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"value":"1756-1841","type":"print"},{"value":"1756-185X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,30]]},"assertion":[{"value":"2018-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-08-13","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}