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However, the relationship between mindfulness and sleep in fibromyalgia patients, who commonly suffer from sleep problems, remains unstudied. We examined the relationship between mindfulness and sleep, and how this relationship may be mediated by depression, anxiety, and pain interference in fibromyalgia patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>We performed a cross\u2010sectional analysis of baseline data from a randomized trial in fibromyalgia patients. We measured mindfulness (Five Facet Mindfulness Questionnaire), sleep quality and disturbance (Pittsburgh Sleep Quality Index [PSQI], PROMIS Sleep Disturbance [PROMIS\u2010SD]), pain interference (PROMIS Pain Interference), and anxiety and depression (Hospital Anxiety and Depression Scale). Pearson correlations were used to examine associations among mindfulness and sleep quality and disturbance. Mediation analysis was conducted to assess whether pain interference, depression, and anxiety mediated the relationship between mindfulness and sleep.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 177 patents with fibromyalgia were included (93% female; mean age 52\u00a0\u00b1\u00a012\u00a0years; body mass index 30\u00a0\u00b1\u00a07\u00a0kg\/m<jats:sup>2<\/jats:sup>; 59% White). Higher mindfulness was associated with better sleep quality and less sleep disturbance (PSQI <jats:italic>r\u00a0<\/jats:italic>=\u00a0\u22120.23, <jats:italic>P\u00a0<\/jats:italic>=\u00a0.002; PROMIS\u2010SD <jats:italic>r\u00a0<\/jats:italic>=\u00a0\u2212.24, <jats:italic>P\u00a0<\/jats:italic>=\u00a0.002) as well as less pain interference (<jats:italic>r\u00a0<\/jats:italic>=\u00a0\u2212.31, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001), anxiety (<jats:italic>r<\/jats:italic>\u00a0=\u00a0\u2212.58, <jats:italic>P\u00a0<\/jats:italic>&lt;\u00a0.001), and depression (<jats:italic>r\u00a0<\/jats:italic>=\u00a0\u22120.54, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.0001). Pain interference, depression, and anxiety mediated the association between mindfulness and sleep quality and disturbance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Higher mindfulness is associated with better sleep in patients with fibromyalgia, with pain interference, depression, and anxiety mediating this relationship. Longitudinal studies are warranted to examine the potential effect of cultivating mindfulness on sleep in fibromyalgia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13756","type":"journal-article","created":{"date-parts":[[2019,11,28]],"date-time":"2019-11-28T01:38:05Z","timestamp":1574905085000},"page":"294-301","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Mindfulness is associated with sleep quality among patients with fibromyalgia"],"prefix":"10.1111","volume":"23","author":[{"given":"Michelle","family":"Park","sequence":"first","affiliation":[{"name":"Tufts University School of Medicine Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Susan and Alan Solomont School of Nursing University of Massachusetts Lowell Lowell MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori Lyn","family":"Price","sequence":"additional","affiliation":[{"name":"Institute for Clinical Research and Health Policy Studies Tufts Medical Center Boston MA USA"},{"name":"Tufts Clinical and Translational Science Institute Tufts University Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raveendhara R.","family":"Bannuru","sequence":"additional","affiliation":[{"name":"Tufts University School of Medicine Boston MA USA"},{"name":"Center for Treatment Comparison and Integrative Analysis Tufts Medical Center Boston MA USA"},{"name":"Center for Complementary and Integrative Medicine &amp; 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