{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T05:00:23Z","timestamp":1790226023000,"version":"4.1.0"},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,6,30]],"date-time":"2020-06-30T00:00:00Z","timestamp":1593475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To describe the prevalence of cognitive impairment and the most affected cognitive domains, employing the Montreal Cognitive Assessment (MoCA) and the Automated Neuropsychological Assessment Metrics (ANAM) of a Latin American primary Sj\u00f6gren's syndrome (pSS) cohort, and compare these patients to secondary Sj\u00f6gren's syndrome (sSS) subjects and controls.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a comparative cross\u2010sectional study of patients with a diagnosis of pSS who fulfilled the American\u2010European Consensus Group 2002 criteria and\/or American College of Rheumatology\/European League Against Rheumatism 2016 criteria; clinical information was evaluated prior to cognitive evaluation, which consisted of a single session in which the MoCA and ANAM were applied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 122 subjects were included in the analysis (51 pSS, 20 sSS and 51 controls); mean age of pSS was 56\u00a0years (SD 10.4), of which 47 (92.15%) were women. Moderate\u2010severe cognitive impairment by MoCA was 17% in pSS, 5% in sSS, and 15% in controls, and by ANAM were 29% in pSS and 10% in sSS (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a0.05). Visuospatial\/executive subdomain in the MoCA was different between the pSS and the control group (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.005). We encountered a statistically significant difference between pSS patients and control scores from the program in 6 of the 7 domains tested by the ANAM.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No difference was found in the prevalence of cognitive impairment between pSS subjects and controls by MoCA. Several subdomain scores differed between groups in both scales. Evaluation of cognitive disorders in patients with SS, even in early stages of the disease, seems advisable but the best strategy is yet to be elucidated.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.13889","type":"journal-article","created":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T01:53:55Z","timestamp":1593568435000},"page":"1019-1023","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Cognitive dysfunction in Sj\u00f6gren\u2019s syndrome using the Montreal Cognitive Assessment Questionnaire and the Automated Neuropsychological Assessment Metrics: A cross\u2010sectional study"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3277-5356","authenticated-orcid":false,"given":"Janett Carmen Luzmila","family":"Riega\u2010Torres","sequence":"first","affiliation":[{"name":"Department of Rheumatology University Hospital \u201cDr Jose Eleuterio Gonzalez\u201d Universidad 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Universidad Aut\u00f3noma de Nuevo Le\u00f3n Monterrey Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4835-7511","authenticated-orcid":false,"given":"Raymundo","family":"Vera\u2010Pineda","sequence":"additional","affiliation":[{"name":"Department of Rheumatology University Hospital \u201cDr Jose Eleuterio Gonzalez\u201d Universidad Aut\u00f3noma de Nuevo Le\u00f3n Monterrey Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5099-0079","authenticated-orcid":false,"given":"Jesus Alberto","family":"Cardenas\u2010de la Garza","sequence":"additional","affiliation":[{"name":"Department of Rheumatology University Hospital \u201cDr Jose Eleuterio Gonzalez\u201d Universidad Aut\u00f3noma de Nuevo Le\u00f3n Monterrey Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Rodriguez\u2010de la 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