{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T16:29:05Z","timestamp":1770222545312,"version":"3.49.0"},"reference-count":53,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,28]],"date-time":"2021-02-28T00:00:00Z","timestamp":1614470400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this randomized controlled study was to investigate the effect of soft\u2010tissue mobilization in patients with ankylosing spondylitis (AS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>Twenty\u2010one patients (mean age 44.57\u00a0\u00b1\u00a010.40\u00a0years) were randomly divided into two groups. There were 13 patients (11 females, 2 males, age 43.69\u00a0\u00b1\u00a09.94\u00a0years) in the intervention group and 8 patients (5 females, 3 males, age 46.00\u00a0\u00b1\u00a011.67\u00a0years) in the control group. In the intervention group, soft\u2010tissue mobilization therapy and 20 spinal mobility exercises were applied. The control group received only 20 spinal mobility exercises. The Bath AS Disease Activity Index (BASDAI), Bath AS Functional Index (BASFI), and Bath AS Metrology Index (BASMI) were used for assessment of disease activity, functional level, and mobility, respectively. Nottingham Health Profile (NHP) for quality of life and Roland Morris Disability Questionnaire (RMDQ) were used to determine disability levels.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We found significant differences between pretreatment and post\u2010treatment scores of BASDAI (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.049); BASFI (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.009; lateral lumbar flexion (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.005), maximal intermalleolar distance (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001) and total score (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001) of BASMI; pain subtest (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.036) and total score (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.036) of NHP; and RMDQ score (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.004) in the intervention group. However, in the control group the BASMI score (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.049) was observed to worsen significantly. Delta values were compared and differences in BASFI (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.039), and in lateral lumbar flexion (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.027), maximal intermalleolar distance (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.045) and total score (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001) of BASMI were significant in favor of intervention group. Only tragus\u2010to\u2010wall distance (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.039) of BASMI was observed to worsen significantly in the control group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We recommend the use of soft\u2010tissue mobilization in addition to the exercises to treat AS patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.14072","type":"journal-article","created":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T01:42:42Z","timestamp":1614562962000},"page":"445-455","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The efficacy of manual soft\u2010tissue mobilization in ankylosing spondylitis: A randomized controlled study"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3209-1499","authenticated-orcid":false,"given":"Elif","family":"Gur Kabul","sequence":"first","affiliation":[{"name":"School of Physical Therapy and Rehabilitation Pamukkale University Denizli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7267-7622","authenticated-orcid":false,"given":"Bilge","family":"Basakci Calik","sequence":"additional","affiliation":[{"name":"School of Physical Therapy and Rehabilitation Pamukkale University Denizli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9369-3381","authenticated-orcid":false,"given":"Mucahit","family":"Oztop","sequence":"additional","affiliation":[{"name":"School of Physical Therapy and Rehabilitation Pamukkale University Denizli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1264-7971","authenticated-orcid":false,"given":"Veli","family":"Cobankara","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Medical Faculty of Pamukkale University Denizli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,2,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780270401"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2008.104018"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24483"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ken506"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/s10165-009-0153-5"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/34.4.301"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(199908)12:4<247::AID-ART3>3.0.CO;2-H"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/32.6.498"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200110)45:5<430::AID-ART362>3.0.CO;2-F"},{"issue":"4","key":"e_1_2_8_11_1","first-page":"763","article-title":"The effect of a home based exercise intervention package on outcome in ankylosing spondylitis: a randomized controlled trial","volume":"29","author":"Sweeney S","year":"2002","journal-title":"J Rheumatol"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1191\/0269215503cr658oa"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.phm.0000163862.89217.fe"},{"issue":"11","key":"e_1_2_8_14_1","first-page":"1067","article-title":"Modern treatment of ankylosing spondylitis","volume":"36","author":"Rehart S","year":"2007","journal-title":"Orthopade"},{"issue":"6","key":"e_1_2_8_15_1","first-page":"S60","article-title":"Physiotherapy in ankylosing spondylitis: what is the evidence?","volume":"20","author":"Linden S","year":"2002","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1100\/tsw.2007.14"},{"issue":"1","key":"e_1_2_8_17_1","first-page":"9","article-title":"Guide to Physical Therapist Practice. Second Edition. American Physical Therapy Association","volume":"81","author":"American Physical Therapy Association","year":"2001","journal-title":"Phys Ther"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1054\/math.1996.0252"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002822.pub3"},{"issue":"12","key":"e_1_2_8_20_1","first-page":"2286","article-title":"A new approach to defining disease status in ankylosing spondylitis: the bath ankylosing spondylitis disease activity index","volume":"21","author":"Garrett S","year":"1994","journal-title":"J Rheumatol"},{"issue":"12","key":"e_1_2_8_21_1","first-page":"2281","article-title":"A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index","volume":"21","author":"Calin A","year":"1994","journal-title":"J Rheumatol"},{"issue":"8","key":"e_1_2_8_22_1","first-page":"1609","article-title":"A new scoring system for the Bath Ankylosing Spondylitis Metrology Index (BASMI)","volume":"22","author":"Jones SD","year":"1995","journal-title":"J Rheumatol"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0277-9536(89)90119-6"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004356-200023010-00004"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198303000-00004"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-200112150-00024"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1982.4.1.16"},{"key":"e_1_2_8_28_1","volume-title":"The Myofascial Release Manual","author":"Manheim C","year":"2008"},{"issue":"8","key":"e_1_2_8_29_1","first-page":"452","article-title":"Myofascial pain: relief by post\u2010isometric relaxation","volume":"65","author":"Lewit K","year":"1984","journal-title":"Arch Phys Med Rehabil"},{"key":"e_1_2_8_30_1","unstructured":"EvjenthO HambergJ.Autostretching: The complete manual of specific stretching. Chattanooga Corp; First Edition (January 1 1991). ISBN\u201010 : 9185934054; ISBN\u201013 : 978\u20109185934058."},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002822.pub2"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269215508101748"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-011-2325-9"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/09638280701270711"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcm.2017.10.002"},{"issue":"2","key":"e_1_2_8_36_1","first-page":"87","article-title":"Ankylosing spondylitis presenting to a chiropractic office: a report of two cases","volume":"44","author":"Mcdermaid C","year":"2000","journal-title":"J Can Chiropr Assoc"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-4754(03)00110-6"},{"issue":"2","key":"e_1_2_8_38_1","first-page":"81","article-title":"Symptomatic improvement in function and disease activity in a patient with ankylosing spondylitis utilizing a course of chiropractic therapy: a prospective case study","volume":"49","author":"Rutherford SM","year":"2005","journal-title":"J Can Chiropr Assoc"},{"key":"e_1_2_8_39_1","first-page":"12","article-title":"The effects of massage on pain, stiffness, and fatigue levels associated with ankylosing spondylitis: a case study","volume":"4","author":"Chunco R","year":"2011","journal-title":"Int J Ther Massage Bodywork"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573397112666161025112750"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.50.11.755"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.4081\/br.2019.6"},{"issue":"1","key":"e_1_2_8_43_1","first-page":"143","article-title":"Proceedings of a consensus conference commissioned by the Canadian Chiropractic Association","volume":"38","author":"Clinical Guidelines for Chiropractic Practice in Canada","year":"1994","journal-title":"J Can Chiropr Assoc"},{"issue":"15","key":"e_1_2_8_44_1","first-page":"720","article-title":"Osteoporosis in ankylosing spondylitis","volume":"25","author":"Toussirot E","year":"1996","journal-title":"Presse Med"},{"issue":"1","key":"e_1_2_8_45_1","first-page":"66","article-title":"Traumatic spinal cord injury as a complication to Ankylosing spondylitis. An extended report","volume":"20","author":"Alaranta H","year":"2002","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/sc.1975.35"},{"issue":"4","key":"e_1_2_8_47_1","first-page":"E90","article-title":"Anterior and posterior fixation of a cervical fracture induced by chiropractic spinal manipulation in ankylosing spondylitis: a case report","volume":"63","author":"Liao CC","year":"2007","journal-title":"J Trauma"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.24025"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2016-000397"},{"issue":"3","key":"e_1_2_8_50_1","first-page":"523","article-title":"Effect of movement velocity on the relationship between training load and the number of repetitions of bench press","volume":"20","author":"Sakamoto A","year":"2006","journal-title":"J Strength Cond Res"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0000000000000800"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/0091-7435(82)90005-6"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.1.3.237"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1037\/0022-006X.50.6.1004"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.14072","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1756-185X.14072","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.14072","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T07:19:10Z","timestamp":1693552750000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1756-185X.14072"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,28]]},"references-count":53,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1111\/1756-185X.14072"],"URL":"https:\/\/doi.org\/10.1111\/1756-185x.14072","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"value":"1756-1841","type":"print"},{"value":"1756-185X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,28]]},"assertion":[{"value":"2020-10-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}