{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T02:38:46Z","timestamp":1768876726730,"version":"3.49.0"},"reference-count":40,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T00:00:00Z","timestamp":1658793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with rheumatoid arthritis (RA) may have nutritional impairment. In RA, muscle loss is associated with an increase in fat tissue, and the patients may not have body mass index (BMI) alterations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To study the nutritional status in a sample of patients with RA in Brazil through mini nutritional assessment (MNA) and electric bioimpedance and its relationship to BMI, functionality, disease activity, and treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seventy\u2010one RA females were included. Chart review was used to obtain epidemiological, clinical, and treatment data. Patients answered the MNA and were submitted to electrical bioimpedance and anthropometric measurements. Disease activity was assessed through simple disease activity index (SDAI), clinical disease activity index (CDAI), and function, through health assessment questionnaire (HAQ).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>According to MNA, 23 (32.4%) patients were at risk for malnutrition and 1 (1.4%) was malnourished. MNA were associated with disease activity and function impairment (SDAI <jats:italic>P<\/jats:italic>\u00a0=\u00a0.02; CDAI <jats:italic>P<\/jats:italic>\u00a0=\u00a0.02, and HAQ <jats:italic>P<\/jats:italic>\u00a0=\u00a0.002) but not with used medications. According to BMI, 76% were overweight or obese. An increased percentage of body fat was found in 98.7% and a lower percentage of lean mass in 95.7%. Disease activity and function were not associated with the percentage of body fat of any used medications, with a lower percentage of body fat in those using abatacept (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Almost one\u2010third of patients had nutritional impairment according to MNA which was associated with disease activity and loss of function. Almost the whole sample had an increased percentage of fat mass and a diminished percentage of muscle mass that could not be linked with disease activity, function or used medications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.14394","type":"journal-article","created":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T08:39:01Z","timestamp":1658824741000},"page":"1145-1151","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Rheumatoid arthritis and nutritional profile: A study in Brazilian females"],"prefix":"10.1111","volume":"25","author":[{"given":"Jo\u00e3o Gabriel Cavazzani","family":"Doubek","sequence":"first","affiliation":[{"name":"Mackenzie Evangelical School of Medicine of Paran\u00e1  Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e1rbara S.","family":"Kahlow","sequence":"additional","affiliation":[{"name":"Rheumatology Unit Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie  Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1234-8093","authenticated-orcid":false,"given":"Renato","family":"Nisihara","sequence":"additional","affiliation":[{"name":"Mackenzie Evangelical School of Medicine of Paran\u00e1  Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7699-3542","authenticated-orcid":false,"given":"Thelma L.","family":"Skare","sequence":"additional","affiliation":[{"name":"Mackenzie Evangelical School of Medicine of Paran\u00e1  Curitiba Brazil"},{"name":"Rheumatology Unit Hospital Universit\u00e1rio Evang\u00e9lico Mackenzie  Curitiba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,7,26]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13041259"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201004-0622OC"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2017-212825"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k1036"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2010.105"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keh321"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1807-59322011000700016"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-009-0017-y"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.1790100103"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.56.5.326"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.14.1624"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23033"},{"issue":"6","key":"e_1_2_11_14_1","first-page":"985","article-title":"Rheumatoid cachexia and cardiovascular disease","volume":"27","author":"Metsios GS","year":"2009","journal-title":"Clin Exp Rheumatol"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1602845"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.3177\/jnsv.66.219"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27584"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-015-0718-8"},{"key":"e_1_2_11_19_1","unstructured":"FerrazMB.Tradu\u00e7\u00e3o para o portugu\u00eas e valida\u00e7\u00e3o do question\u00e1rio para avaliar a capacidade funcional \u201cStanford Health Assessment Questionnaire\u201d. 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