{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:29:22Z","timestamp":1747182562715,"version":"3.40.5"},"reference-count":35,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T00:00:00Z","timestamp":1663804800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To study the economic impact of systemic sclerosis (SSc) in the patients attending Rheumatology clinics in Waikato Hospital, Hamilton, New Zealand (NZ). There is currently no bottom\u2010up data on this in NZ.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This is a retrospective cross\u2010sectional questionnaire\u2010based study, including demographics, costs related to SSc, quality of life measures including the short\u2010form survey (SF\u201036) the scleroderma health assessment questionnaire\u2010visual analog scale (SHAQ\u2010VAS), the NZ index of Deprivation (NZiDep), and work limitations questionnaire (WLQ). Direct health costs include patient\u2010reported costs and costs incurred by the public health system. Indirect costs include calculated loss of work productivity. Comparisons were made between age, gender, disease duration, and disease subtype (diffuse, limited, and overlap syndromes).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Participants fulfilled the 2013 ACR\/EULAR criteria for SSc. The study was completed by 86 (65.5%) patients, 77 (90%) were females, 19 (22%) had diffuse cutaneous systemic sclerosis (dcSSc), 72 (83%) were NZ European (NZE), seven(8%) were M\u0101ori or NZE\/M\u0101ori. Seventy\u2010six (41.8%) were employed. The average total costs for 6\u00a0months were NZ$\u00a0444.50 with the highest costs in the dcSSc sub\u2010group at NZ$\u00a0598.00. The costs incurred by the Hospital for the 2018\/2019 fiscal year was NZ$\u00a03091 per patient. The SF\u201036 score was lower compared with the general population, mean SHAQ was 0.82. Mean summative WLQ scores were: Time management 21.7, Physical demands 62.5, Interpersonal 23.6, Output demands 23.8. The calculated percentage productivity loss was 46.5%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>This study has shown high health\u2010related costs of SSc in NZ, with reduction in employment, work productivity, and quality of life. The contributors to the costs included physical disability and loss of productivity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.14433","type":"journal-article","created":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T13:04:26Z","timestamp":1663851866000},"page":"1386-1394","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Direct and indirect health\u2010related costs of systemic sclerosis in New Zealand"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4784-5898","authenticated-orcid":false,"given":"Sree Deepika","family":"Padala","sequence":"first","affiliation":[{"name":"Rheumatology Department Waikato Hospital Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunhuan","family":"Lao","sequence":"additional","affiliation":[{"name":"Senior Research Fellow, Medical Research Centre, School of Health University of Waikato Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamal","family":"Solanki","sequence":"additional","affiliation":[{"name":"Rheumatology Department Waikato Hospital Hamilton New Zealand"},{"name":"Waikato Clinical School University of Auckland Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas","family":"White","sequence":"additional","affiliation":[{"name":"Rheumatology Department Waikato Hospital Hamilton New Zealand"},{"name":"Waikato Clinical School University of Auckland Hamilton New Zealand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,9,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/03009742.2014.976653"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.5114\/reum.2016.64906"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.5604\/12321966.1233570"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2009.11.003"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keg033"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2008.06.002"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24676"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keq165"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kex182"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-019-1842-x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11050911"},{"key":"e_1_2_6_13_1","unstructured":"<Economic\u2010Cost\u2010of\u2010Arthritis\u2010in\u2010New\u2010Zealand\u20102018.pdf>"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38098"},{"issue":"1","key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.20452\/pamw.1487","article-title":"Very early diagnosis of systemic sclerosis","volume":"122","author":"Bellando\u2010Randone S","year":"2012","journal-title":"Pol Arch Med Wewn"},{"issue":"2","key":"e_1_2_6_16_1","first-page":"202","article-title":"Scleroderma (systemic sclerosis): classification, subsets and pathogenesis","volume":"15","author":"LeRoy EC","year":"1988","journal-title":"J Rheumatol"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(01)00424-3"},{"issue":"11","key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"S98","DOI":"10.1002\/acr.20598","article-title":"Measures of systemic sclerosis (scleroderma): health assessment questionnaire (HAQ) and scleroderma HAQ (SHAQ), physician\u2010 and patient\u2010rated global assessments, symptom burden index (SBI), University of California, los Angeles, scleroderma clinical trials consortium gastrointestinal scale (UCLA SCTC GIT) 2.0, baseline dyspnea index (BDI) and transition dyspnea index (TDI) (Mahler's index), Cambridge pulmonary hypertension outcome review (CAMPHOR), and Raynaud's condition score (RCS)","volume":"63","author":"Pope J","year":"2011","journal-title":"Arthritis Care Res"},{"volume-title":"SF36 Health Survey: Manual and Interpretation Guide","year":"1993","author":"Ware J","key":"e_1_2_6_19_1"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4160-4978-4.00005-3"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2005.08.008"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.11403"},{"volume-title":"Pharmaceutical schedule","year":"2018","author":"PHARMAC","key":"e_1_2_6_23_1"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.180042"},{"key":"e_1_2_6_25_1","unstructured":"<M\u0101ori ethnic group population estimates 2006\u201318: Methods and results | Stats NZ.pdf>"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kex362"},{"key":"e_1_2_6_27_1","unstructured":"Mean and median annual personal income in New Zealand. 2018."},{"issue":"1506","key":"e_1_2_6_28_1","first-page":"10","article-title":"The costs associated with ankylosing spondylitis\/axial spondyloarthritis in Aotearoa\/New Zealand","volume":"132","author":"White D","year":"2019","journal-title":"NZ Med J"},{"issue":"6","key":"e_1_2_6_29_1","first-page":"1006","article-title":"Work limitations among working persons with rheumatoid arthritis: results, reliability, and validity of the work limitations questionnaire in 836 patients","volume":"32","author":"Walker N","year":"2005","journal-title":"J Rheumatol"},{"key":"e_1_2_6_30_1","unstructured":"<SF\u201036_MOH.pdf>"},{"key":"e_1_2_6_31_1","unstructured":"<sf36\u2010profiles\u2010sex\u2010total\u2010population.pdf>"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.20048"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2021.101667"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24086"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.22167"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-016-0789-y"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.14433","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1756-185X.14433","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.14433","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,4]],"date-time":"2024-10-04T11:46:22Z","timestamp":1728042382000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1756-185X.14433"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,22]]},"references-count":35,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1111\/1756-185X.14433"],"URL":"https:\/\/doi.org\/10.1111\/1756-185x.14433","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"type":"print","value":"1756-1841"},{"type":"electronic","value":"1756-185X"}],"subject":[],"published":{"date-parts":[[2022,9,22]]},"assertion":[{"value":"2022-04-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}