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Serum ferritin levels have commonly been used to diagnose s\u2010JIA because they increase in patients with this condition by more than 5 times their normal value. However, there are no definite biomarkers for s\u2010JIA, which makes the clinical diagnosis of s\u2010JIA difficult. We report a case of s\u2010JIA in which interleukin (IL)\u201018 elevation was observed before ferritin elevation at the early phase of s\u2010JIA. We propose serum IL\u201018 levels as a more useful biomarker for the early diagnosis of s\u2010JIA compared to serum ferritin levels.<\/jats:p>","DOI":"10.1111\/1756-185x.14534","type":"journal-article","created":{"date-parts":[[2022,12,17]],"date-time":"2022-12-17T04:48:53Z","timestamp":1671252533000},"page":"551-553","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Serum interleukin\u201018 level as a possible early diagnostic marker of systemic juvenile idiopathic arthritis"],"prefix":"10.1111","volume":"26","author":[{"given":"Kento","family":"Souma","sequence":"first","affiliation":[{"name":"Department of Pediatrics Kakogawa Central City Hospital  Kakogawa City, Hyogo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junya","family":"Fujimura","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Kakogawa Central City Hospital  Kakogawa City, Hyogo 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