{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T22:23:55Z","timestamp":1786487035213,"version":"build-2736575974"},"reference-count":12,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T00:00:00Z","timestamp":1677542400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82074246"],"award-info":[{"award-number":["82074246"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report the case of a 59\u2010year\u2010old female patient, presenting with pustular rash on both hands and pain in the lumbosacral part and left lower limb. A magnetic resonance imaging examination of the left leg was undertaken and the result showed that a malignant lesion with bone destruction of the left femoral shaft could not be excluded. Subsequently, bone tumor was excluded by pathological examination. Lung computed tomography scan showed patchy consolidation and cord shadow in the middle left lung. Subsequently, lung cancer was excluded by pathological examination, and the histopathological changes of lung were consistent with those of organized pneumonia. Blood tests revealed elevated C\u2010reactive protein and erythrocyte sedimentation rate. Antinuclear antibody, rheumatoid factor, and human leukocyte antigen\u2010B27 were unremarkable. Whole body bone scintigraphy via technetium 99m\u2010methyl diphosphonate showed increased radionuclide uptake in the left middle femur. Based on her clinical manifestations, imaging results and bone scintigraphy, the patient was diagnosed as having synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome. Loxoprofen and <jats:italic>Tripterygium wilfordii<\/jats:italic> Hook F led to impressive clinical and radiologic improvement.<\/jats:p>","DOI":"10.1111\/1756-185x.14631","type":"journal-article","created":{"date-parts":[[2023,2,28]],"date-time":"2023-02-28T12:39:56Z","timestamp":1677587996000},"page":"1586-1589","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Synovitis, acne, pustulosis, hyperostosis, osteitis syndrome with invisible organizing pneumonia: A case report"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2264-4897","authenticated-orcid":false,"given":"Tianlun","family":"Kang","sequence":"first","affiliation":[{"name":"Department of Rheumatology Dongfang Hospital Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajing","family":"Xi","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Dongfang Hospital Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingzi","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Dongfang Hospital Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shufeng","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Fangshan Hospital Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1236-6849","authenticated-orcid":false,"given":"Xiujuan","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Dongfang Hospital Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8527-1680","authenticated-orcid":false,"given":"Chen","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Fangshan Hospital Beijing University of Chinese Medicine  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,2,28]]},"reference":[{"issue":"5","key":"e_1_2_6_2_1","first-page":"613","article-title":"Le syndrome synovite\u2010acn\u00e9\u2010pustulose\u2010hyperostose\u2010ost\u00e9ite (SAPHO) [Synovitis\u2010acne\u2010pustulosis\u2010hyperostosis\u2010osteitis (SAPHO) syndrome]","volume":"115","author":"Benhamou C","year":"1988","journal-title":"Ann Dermatol 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