{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:29:58Z","timestamp":1747182598476,"version":"3.40.5"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T00:00:00Z","timestamp":1679443200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We aimed to quantitatively analyze lung parenchymal changes in Beh\u00e7et's patients and to detect early parenchymal quantitative changes that occur in the absence of positive visual radiological findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In our study, a total of 31 patients with Beh\u00e7et's disease, 17 with positive radiological findings and 14 patients without positive radiological findings, and a control group of 33 individuals were evaluated. The automatic program determined lung volumes, lung densities, and opacity volume percentages by evaluating the contrast\u2010enhanced lung computed tomography scans.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The total lung volume was 3632.98\u00a0\u00b1\u20091100.53\u2009mL in the Beh\u00e7et's disease patient group and 4925.70\u2009\u00b1\u20091098.88\u2009mL in the control group, and there was a significant decrease in the total lung volume in Beh\u00e7et's disease patients (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.0001). The mean lung density was \u2212723.73\u2009\u00b1\u200965.16 in the Beh\u00e7et's disease patient group and \u2212767.35\u2009\u00b1\u200941.17 in the control group, and there was a significant increase in the mean density in the Beh\u00e7et's patients (<jats:italic>P<\/jats:italic>\u00a0=\u20090.0023). A significantly higher correlation was observed between lung density and lung volume in Beh\u00e7et's patients (<jats:italic>P<\/jats:italic>\u00a0&lt;\u20090.0001, <jats:italic>r<\/jats:italic>\u00a0=\u2009\u22120.795). The lung volume of Beh\u00e7et's disease patients with negative radiological findings was significantly lower than that of the control group (<jats:italic>P<\/jats:italic>\u00a0=\u20090.0342).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Lung volumetric changes in Beh\u00e7et's disease patients are the quantitative data most affected by the disease. In addition, lung volume decreases in Beh\u00e7et's patients who do not have visual parenchymal involvement.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.14673","type":"journal-article","created":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T12:29:09Z","timestamp":1679488149000},"page":"917-921","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Quantitative analysis of lung parenchymal involvement in Beh\u00e7et's disease by the novel automatic program"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9184-8730","authenticated-orcid":false,"given":"G\u00f6khan","family":"Polat","sequence":"first","affiliation":[{"name":"Department of Radiology, Medical Faculty Ataturk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Alperen","family":"Tezcan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Medical Faculty Ataturk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merve","family":"Polat","sequence":"additional","affiliation":[{"name":"Department of Health Physics, Health Sciences Institute Karadeniz Technical University  Trabzon Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Furkan","family":"Barut\u00e7ugil","sequence":"additional","affiliation":[{"name":"Department of Radiology, Medical Faculty Ataturk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuncay","family":"Bayram","sequence":"additional","affiliation":[{"name":"Department of Health Physics, Health Sciences Institute Karadeniz Technical University  Trabzon Turkey"},{"name":"Department of Physics Karadeniz Technical University  Trabzon Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Recep","family":"Sade","sequence":"additional","affiliation":[{"name":"Department of Radiology, Medical Faculty Ataturk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zlem","family":"Kuda\u015f","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Medical Faculty Ataturk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Berhan","family":"Pirimo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Radiology, Medical Faculty Ataturk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elshad","family":"\u0130smailova","sequence":"additional","affiliation":[{"name":"Department of Radiology, Medical Faculty Ataturk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Yal\u00e7\u0131n","sequence":"additional","affiliation":[{"name":"Department of Radiology, Medical Faculty Ataturk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emrah","family":"Meletlio\u011flu","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering, Institute of Science Ataturk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Kahraman","sequence":"additional","affiliation":[{"name":"Department of Radiology Erzurum City Hospital  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,3,22]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.243035091"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.56.7.572"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.95.3.585"},{"issue":"3","key":"e_1_2_9_5_1","first-page":"402","article-title":"Vascular involvement in Behcet's disease","volume":"19","author":"Ko\u00e7 Y","year":"1992","journal-title":"J Rheumatol"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/146.1.232"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004080000019"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12626"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.2763"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.5578\/tt.27936"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.164.1.7998568"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20150992"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0761-8425(05)85731-6"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/crj.12153"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000131"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.2174\/1573405617999210112193856"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.172.3.10063870"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.e31"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-006-0508-7"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12112868"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.14673","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1756-185X.14673","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.14673","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T17:44:18Z","timestamp":1692726258000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1756-185X.14673"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,22]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1111\/1756-185X.14673"],"URL":"https:\/\/doi.org\/10.1111\/1756-185x.14673","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"type":"print","value":"1756-1841"},{"type":"electronic","value":"1756-185X"}],"subject":[],"published":{"date-parts":[[2023,3,22]]},"assertion":[{"value":"2023-01-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-10","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}