{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T06:54:14Z","timestamp":1769756054032,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T00:00:00Z","timestamp":1683504000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>SARS\u2010CoV2 primarily affects the respiratory system but a hyperinflammatory response leading to multisystem inflammatory syndrome \u2013 children (MIS\u2010C), immune dysfunction and various autoimmune manifestations has also been noted. Autoimmunity depends on various factors, including genetic predisposition, environmental factors, immune dysregulation and infections acting as triggers like Epstein\u2010Barr virus, cytomegalovirus, human immunodeficiency virus, hepatitis B. Molecular mimicry, bystander T\u2010cell activation and persistence of viral infection are the main mechanisms behind these manifestations. We present here 3 cases of newly diagnosed connective tissue disease with high titers of COVID19 immunoglobulin G antibody in children. A 9\u2010year\u2010old girl with fever, oliguria and malar rash (prior history of sore throat) and a 10\u2010year\u2010old girl with fever for 2\u2009weeks and choreoathetoid movements were diagnosed as systemic lupus erythematosus (SLE) nephritis (stage 4) and neuropsychiatric SLE, respectively as per European League Against Rheumatism \/ American College of Rheumatology 2019 criteria. An 8\u2010year\u2010old girl with fever, joint pain and respiratory distress (a recent contact with a positive COVID19 patient) presented with altered sensorium, Raynaud's phenomenon noted, and eventually diagnosed as mixed connective tissue disease as per Kusukawa criteria. The immune\u2010mediated manifestations post\u2010COVID infection are a de\u2010novo phenomenon which necessitates further workup as not many studies exist in the pediatric population.<\/jats:p>","DOI":"10.1111\/1756-185x.14724","type":"journal-article","created":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T05:02:07Z","timestamp":1683608527000},"page":"2288-2293","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Autoimmune diseases post\u2010COVID 19 infection in children in intensive care unit: A case series"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6468-2413","authenticated-orcid":false,"given":"Subhadipa","family":"Das","sequence":"first","affiliation":[{"name":"Department of Paediatrics Nilrantan Sircar Medical College  Kolkata West Bengal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3906-2271","authenticated-orcid":false,"family":"Parul","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Nilrantan Sircar Medical College  Kolkata West Bengal India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7961-2672","authenticated-orcid":false,"given":"Moumita","family":"Samanta","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Nilrantan Sircar Medical College  Kolkata West Bengal 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