{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T03:13:21Z","timestamp":1778901201721,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T00:00:00Z","timestamp":1688774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To explore the performance and effect of dual\u2010energy computed tomography (CT) and ultrasound in the diagnosis of gouty arthritis and to provide a reference for the clinical diagnosis of gouty arthritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis of 76 patients with gouty arthritis admitted to the hospital from June 2020 to June 2022 was conducted. Patients were diagnosed with gouty arthritis using ultrasound and dual\u2010energy CT technology. The accuracy of diagnosis by different imaging techniques was analyzed along with the imaging findings of ultrasound and dual\u2010energy CT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010six patients, 60 men and 16 women, ranging in age from 20 to 77\u2009years (mean age 50.8\u2009\u00b1\u200910.92\u2009years), presented with uric acid levels of 254.1\u2013720.05\u2009\u03bcmol\/L (mean 482.17\u2009\u00b1\u2009105.06\u2009\u03bcmol\/L) and C\u2010reactive protein levels ranging from 4.25 to 10.3\u2009mg\/L. The receiver operating characteristic curve showed that the area under the curve and specificity of serum uric acid were higher by dual\u2010energy CT than those of ultrasound in the diagnosis of gouty arthritis. The dual\u2010energy CT detection rate of tophi was significantly higher than the ultrasound detection rate (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). For inflammatory effusion and synovial thickening, the ultrasound detection rates were significantly higher than the dual\u2010energy CT detection rates (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). Regarding soft\u2010tissue edema, the detection rate of the two methods was not significantly different (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Compared with ultrasound, dual\u2010energy CT has increased accuracy in the diagnosis of gouty arthritis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.14792","type":"journal-article","created":{"date-parts":[[2023,7,8]],"date-time":"2023-07-08T10:04:18Z","timestamp":1688810658000},"page":"1697-1703","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Comparison of diagnostic efficacy of dual\u2010energy <scp>CT<\/scp> and ultrasound in gouty arthritis"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6604-3693","authenticated-orcid":false,"given":"Xiulin","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Clinical Medicine Fenyang College of Shanxi Medical University  Fenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huanling","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Nursing Fenyang College of Shanxi Medical University  Fenyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liyun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Shanxi Bethune Hospital  Taiyuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liqing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Shanxi Bethune Hospital  Taiyuan China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,7,8]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00569-9"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2020.02.014"},{"issue":"6","key":"e_1_2_13_4_1","first-page":"462","article-title":"Application of musculoskeletal ultrasound in asymptomatic hyperuricemia and gout. 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