{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T19:30:01Z","timestamp":1786563001877,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Given reports of increased prevalence of PTSD symptoms at COVID\u201019 pandemic onset, we aimed to assess the prevalence of posttraumatic stress disorder (PTSD) symptoms at pandemic onset in individuals with and without systemic autoimmune rheumatic disease (SARD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In May 2020, we invited 6678 patients to complete the Brief Trauma Questionnaire and the Posttraumatic Stress Disorder Checklist (PCL\u20105), validated PTSD symptom screenings. We compared responses from patients with and without SARD using multivariable logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We received 1473 responses (22% response rate) from 5\/2020 to 9\/2021 (63 with prior PTSD diagnoses, 138 with SARD history). The SARD population was more female (\n                      <jats:italic>p<\/jats:italic>\n                      .0001) and had a higher baseline prevalence of stress disorders (56% vs. 43%,\n                      <jats:italic>p<\/jats:italic>\n                      .004). SARD subjects reported more experiences with life\u2010threatening illness, 60%, versus 53% among those without SARD (\n                      <jats:italic>p<\/jats:italic>\n                      .13), and more antidepressant or anxiolytic medication use pre\u2010pandemic (78% vs. 59%,\n                      <jats:italic>p<\/jats:italic>\n                      .0001). Adjusting for pre\u2010pandemic PTSD diagnosis, younger age and history of stress disorder were the most significant predictors of PCL\u20105 positivity. There were no significant differences in PCL\u20105 score or positivity among those with or without SARD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this population, patients with SARD had a higher pre\u2010COVID\u201019 prevalence of stress\u2010related conditions, but it was not the case that they had an increased risk of PTSD symptoms in the early pandemic. Younger individuals, those with baseline depression, anxiety, or adjustment disorders, and those taking antidepressant or anxiolytic medications were more likely to have PTSD symptoms in the first waves of the COVID\u201019 pandemic.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1756-185x.14974","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T17:01:24Z","timestamp":1700586084000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Posttraumatic stress disorder symptoms in systemic autoimmune rheumatic disease patients during the early COVID\u201019 pandemic"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1701-6258","authenticated-orcid":false,"given":"Emily G.","family":"Oakes","sequence":"first","affiliation":[{"name":"Division of Rheumatology, Inflammation, and Immunity Brigham and Women's Hospital  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Ellrodt","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Inflammation, and Immunity Brigham and Women's Hospital  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeong","family":"Yee","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Inflammation, and Immunity Brigham and Women's Hospital  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongshu","family":"Guan","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Inflammation, and Immunity Brigham and Women's Hospital  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura D.","family":"Kubzansky","sequence":"additional","affiliation":[{"name":"Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karestan C.","family":"Koenen","sequence":"additional","affiliation":[{"name":"Harvard T.H. Chan School of Public Health  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8972-9388","authenticated-orcid":false,"given":"Karen H.","family":"Costenbader","sequence":"additional","affiliation":[{"name":"Division of Rheumatology, Inflammation, and Immunity Brigham and Women's Hospital  Boston Massachusetts USA"},{"name":"Harvard Medical School  Boston Massachusetts 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