{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:10:57Z","timestamp":1791807057789,"version":"4.3.4"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T00:00:00Z","timestamp":1708992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the relationship between anatomical variants of sacroiliac joint (SIJ) and subchondral changes detected in magnetic resonance enterography (MRE) in patients with Crohn's disease (CD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a retrospective study of 60 CD patients, who were divided into two groups: with (<jats:italic>n<\/jats:italic>\u2009=\u200916) and without SIJ (<jats:italic>n<\/jats:italic>\u2009=\u200944) involvement, depending on the presence of inflammatory (bone marrow edema) and structural changes (sclerosis and erosions) in MRE. Anatomical variants of SIJ were assessed in CT of the abdomen and\/or pelvis, distinguishing typical form with convex iliac surface and atypical forms. Univariate and multivariate analyses were performed to reveal an association between joint changes and forms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Our study included 60 patients (38 males; mean age 38.72\u2009years\u2009\u00b1\u200913.33). Patients with SIJ changes were older (<jats:italic>p<\/jats:italic>\u2009=\u2009.044). No significant differences in CD localization and behavior were found. The most common SIJ lesions were structural changes (in 75% of patients); the main atypical form was the iliosacral complex. The univariate and multivariate analyses showed a significant association of atypical forms with total subchondral changes (odds ratio [OR]: 3.429, 95% confidence interval [CI] 1.043\u201311.268; <jats:italic>p<\/jats:italic>\u2009=\u2009.042; OR: 5.066, 95% CI: 1.273\u201320.167; <jats:italic>p<\/jats:italic>\u2009=\u2009.021, respectively), and with structural changes (OR: 4.185, 95% CI: 1.155\u201315.160; <jats:italic>p<\/jats:italic>\u2009=\u2009.029; OR: 5.986, 95% CI: 1.293\u201327.700; <jats:italic>p<\/jats:italic>\u2009=\u2009.022, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Atypical forms of SIJ are a risk factor for the occurrence of structural joint changes in CD patients. An association between bone marrow edema and atypical forms was not found.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.15046","type":"journal-article","created":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T05:19:28Z","timestamp":1709097568000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association between sacroiliac joint forms and subchondral changes in patients with Crohn's disease"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-6527-5091","authenticated-orcid":false,"given":"Oksana","family":"Melekh","sequence":"first","affiliation":[{"name":"University Clinic for Radiology and Nuclear Medicine University Hospital Magdeburg  Magdeburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Barajas\u00a0Ordonez","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology University 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