{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T22:31:57Z","timestamp":1783636317767,"version":"3.55.0"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T00:00:00Z","timestamp":1707436800000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The purpose of this study was to evaluate the prevalence of idiopathic intracranial hypertension (IIH) in fibromyalgia (FMS) patients by utilizing ultrasound to measure the optic nerve sheath diameter (ONSD), a marker of elevated intracranial pressure and also to investigate the relationship with function, fatigue, quality of life (QOL), central sensitization (CS) and neuropathic pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study encompassed 80 female FMS patients and 75 healthy controls. Ultrasound was employed to measure the average ONSD in both groups. Conditions potentially elevating intracranial pressure were ruled out following neurological assessments. Pain (via visual analog scale, VAS), function (revised Fibromyalgia Impact Questionnaire, r\u2010FIQ), QOL (Short Form\u201036, SF\u201036), fatigue (fatigue severity scale, FACIT), CS (Central Sensitization Scale), and neuropathic pain (Douleur Neuropathique\u20104) were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average ONSD was significantly higher in the patient group than the control group. Patients with ONSD &gt;5.5\u2009mm consistent with IIH were categorized as Group 1 (<jats:italic>n<\/jats:italic>\u2009=\u200954, 67.5%), while those with a diameter of 5.5\u2009mm and below\u2010formed Group 2. VAS pain (<jats:italic>p<\/jats:italic>\u2009=\u2009.033) and FIQ\u2010R scores (<jats:italic>p<\/jats:italic>\u2009=\u2009.033) were significantly higher in Group 1 than Group 2. Headache was found more common in Group 1.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study unveils a substantial occurrence (67.5%) of IIH in FMS patients, suggesting shared pathophysiological mechanisms contributing to symptoms like fatigue, headache, and cognitive dysfunction. Additionally, these findings implicate heightened functional impairment, CS, headache, and fatigue in FMS patients with IIH.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.15066","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T12:21:55Z","timestamp":1707481315000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Frequency of idiopathic intracranial hypertension with ultrasound in patients with fibromyalgia: Relation with function, central sensitization, and neuropathic pain"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2950-8778","authenticated-orcid":false,"given":"Serta\u00e7","family":"Ketenci","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation and Department of Rheumatology, Medical Faculty Ondokuz Mayis University  Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bora","family":"Uzuner","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation and Department of Algology, Medical Faculty Ondokuz Mayis University  Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilek","family":"Durmu\u015f","sequence":"additional","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Medical Faculty Ondokuz Mayis University  Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Polat","sequence":"additional","affiliation":[{"name":"Department of Neurology, Medical Faculty Ondokuz Mayis University  Samsun Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,2,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-020-00506-w"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2021.110624"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2006.12.009"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.00828"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S186878"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2017.12.006"},{"key":"e_1_2_11_8_1","first-page":"28","article-title":"Looking for idiopathic intracranial hypertension in patients with chronic fatigue syndrome","volume":"1","author":"Higgins N","year":"2013","journal-title":"J Obs Pain Med"},{"issue":"1","key":"e_1_2_11_9_1","first-page":"85","article-title":"Assessment of optic nerve sheath diameter in healthy adults in Turkey","volume":"11","author":"Gokcen E","year":"2021","journal-title":"Sakarya Med J"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-018-4316-7"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-010-1546-8"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.endinu.2018.01.010"},{"key":"e_1_2_11_13_1","first-page":"11","article-title":"Reliability and validity of the Turkish version of short form 36 (SF\u201036) in patients with rheumatoid arthritis","volume":"2","author":"Kaya BB","year":"2018","journal-title":"J Surg Med"},{"issue":"36","key":"e_1_2_11_14_1","first-page":"518","article-title":"Validity and reliability of the Turkish version of the central sensitization inventory","volume":"18","author":"D\u00fczce Kele\u015f E","year":"2021","journal-title":"Arch Rheumatol"},{"issue":"59","key":"e_1_2_11_15_1","first-page":"44","article-title":"Neuropathic pain and its relationship with clinical findings in patients with fibromyalgia","volume":"11","author":"Akaltun MS","year":"2020","journal-title":"Noro Psikiyatr Ars"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/17562864211069744"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22083891"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar2005"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41220"},{"key":"e_1_2_11_20_1","unstructured":"GluckmanSJ.Clinical features and diagnosis of myalgic encephalomyelitis\/chronic fatigue syndrome. 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