{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:44:42Z","timestamp":1789343082174,"version":"build-2803163510"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,20]],"date-time":"2024-03-20T00:00:00Z","timestamp":1710892800000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006197","name":"Fonden til L\u00e6gevidenskabens Fremme","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006197","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005860","name":"Helsefonden","doi-asserted-by":"publisher","award":["21\u2010B\u20100125"],"award-info":[{"award-number":["21\u2010B\u20100125"]}],"id":[{"id":"10.13039\/501100005860","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001734","name":"K\u00f8benhavns Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001734","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008368","name":"Gigtforeningen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008368","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005111","name":"Rigshospitalet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005111","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006088","name":"Direkt\u00f8r Emil C. Hertz og Hustru Inger Hertz Fond","doi-asserted-by":"publisher","award":["KJR 13016"],"award-info":[{"award-number":["KJR 13016"]}],"id":[{"id":"10.13039\/501100006088","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To investigate the potential associations between functional capacity, muscle strength, body composition, and disease\u2010related measures and quality of life in patients with myositis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Baseline measures of functional capacity (functional index 3 (FI3), 2\u2010minute walk test (2MWT), timed up and go (TUG) and 30\u2010s sit\u2010to\u2010stand (30\u2010STS)), muscle strength (incl. leg and handgrip strength), maximal leg extensor power, body composition (appendicular lean mass, fat percentage\/mass) and disease\u2010related measures (disease activity &amp; damage core sets) were examined for their associations with quality of life (physical\u2010 and mental component summary scores, Short Form 36 questionnaire (SF\u201036)) by means of Spearman's correlation analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 32 patients with myositis were included. Positive correlations between SF\u201036 physical component summary score (PCS) and FI3, 30\u2010STS, TUG, 2MWT, leg extensor power, leg strength, bench press strength, and handgrip strength were observed. In contrast, fat percentage and fat mass correlated negatively with PCS. In disease\u2010related measures, Extramuscular global assessment, health assessment questionnaire, physician global damage, and patient global damage scores were negatively associated with SF\u201036 PCS. No correlations to the mental component summary score of SF\u201036 were observed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>All measures of functional capacity were positively related to the SF\u201036 physical component summary score, indicating higher functional capacity positively affects quality of life in patients with myositis. Health assessment questionnaire and patient global damage scores demonstrated the strongest correlations with SF\u201036 physical component summary scores, further supporting these patient\u2010reported outcomes as viable monitoring tools in patients with myositis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.15132","type":"journal-article","created":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T06:39:27Z","timestamp":1711003167000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Quality of life in patients with myositis is associated with functional capacity, body composition, and disease activity\u2014Baseline data from a randomized controlled trial"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4232-6079","authenticated-orcid":false,"given":"Kasper Yde","family":"Jensen","sequence":"first","affiliation":[{"name":"Copenhagen Research Center for Autoimmune Connective Tissue Diseases (COPEACT), Center for Rheumatology and Spine Diseases Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9773-7361","authenticated-orcid":false,"given":"Per","family":"Aagaard","sequence":"additional","affiliation":[{"name":"Department of Sports Science and Clinical Biomechanics University of Southern Denmark Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Suetta","sequence":"additional","affiliation":[{"name":"Geriatric Research Unit, Department of Geriatric and Palliative Medicine Copenhagen University Hospital, Bispebjerg and Frederiksberg Copenhagen Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Health Sciences University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob L.","family":"Nielsen","sequence":"additional","affiliation":[{"name":"Department of Sports Science and Clinical Biomechanics University of Southern Denmark Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik D.","family":"Schr\u00f8der","sequence":"additional","affiliation":[{"name":"Department of Pathology Odense University Hospital Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Gr\u00f8nset","sequence":"additional","affiliation":[{"name":"Department of Occupational Therapy and Physiotherapy Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Casper","family":"Simonsen","sequence":"additional","affiliation":[{"name":"Centre for Physical Activity Research Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise P.","family":"Diederichsen","sequence":"additional","affiliation":[{"name":"Copenhagen Research Center for Autoimmune Connective Tissue Diseases (COPEACT), Center for Rheumatology and Spine Diseases Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Health Sciences University of Copenhagen Copenhagen Denmark"},{"name":"Department of Rheumatology Odense University Hospital Odense Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,20]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12524"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408363.2021.2000584"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-017-3706-6"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.10.016"},{"issue":"10","key":"e_1_2_13_6_1","first-page":"2230","article-title":"Polymyositis and dermatomyositis: short term and longterm outcome, and predictive factors of prognosis","volume":"28","author":"Marie I","year":"2001","journal-title":"J Rheumatol"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.14120"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-014-2685-0"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25603"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2020-043793"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2017-000507"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.40320"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200702000-00007"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.191374"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keac244"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1991.tb01616.x"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/59.11.1207"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00713504"},{"issue":"2","key":"e_1_2_13_19_1","doi-asserted-by":"crossref","first-page":"342","DOI":"10.70252\/RAWV7859","article-title":"Central hemodynamics measured during 5 repetition maximum free weight resistance exercise","volume":"11","author":"Howard JS","year":"2018","journal-title":"Int J Exerc Sci"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afr051"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12477"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000117161.66394.07"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000000289"},{"key":"e_1_2_13_24_1","unstructured":"vanHeesV FangZ ZhaoJ et\u00a0al.GGIR: Raw Accelerometer Data Analysis. R package version 2.9\u201302023."},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab236"},{"key":"e_1_2_13_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20532"},{"key":"e_1_2_13_27_1","doi-asserted-by":"publisher","DOI":"10.2307\/1422689"},{"key":"e_1_2_13_28_1","volume-title":"RStudio: Integrated Development Environment for R","author":"R CoreTeam","year":"2015"},{"key":"e_1_2_13_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.SMJ.0000157534.08859.4B"},{"key":"e_1_2_13_30_1","doi-asserted-by":"publisher","DOI":"10.3109\/13685538.2010.502267"},{"key":"e_1_2_13_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12737"},{"key":"e_1_2_13_32_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000001683"},{"key":"e_1_2_13_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-014-9714-4"},{"key":"e_1_2_13_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2018.11.007"},{"key":"e_1_2_13_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2318-13-74"},{"key":"e_1_2_13_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab805"},{"key":"e_1_2_13_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0193377"},{"key":"e_1_2_13_38_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009740600907881"},{"key":"e_1_2_13_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keab700"},{"key":"e_1_2_13_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2020.06.014"},{"key":"e_1_2_13_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2021.03.018"}],"container-title":["International Journal of Rheumatic Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1756-185X.15132","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T19:31:27Z","timestamp":1731612687000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1756-185X.15132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1111\/1756-185X.15132"],"URL":"https:\/\/doi.org\/10.1111\/1756-185x.15132","archive":["Portico"],"relation":{},"ISSN":["1756-1841","1756-185X"],"issn-type":[{"value":"1756-1841","type":"print"},{"value":"1756-185X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"2024-01-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e15132"}}