{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T13:27:39Z","timestamp":1789133259105,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T00:00:00Z","timestamp":1729209600000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To determine the incidence and health outcomes for juvenile idiopathic inflammatory myopathy (JIIM) in a long\u2010term whole\u2010population study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included patients under 18\u2009years hospitalized in Western Australia (WA) from 1985 and 2015 with incident JIIM as defined by pertinent diagnostic codes for dermatomyositis (JDM) polymyositis (JPM), other JIIM and overlap myositis (JOM). We compared clinical outcomes and modified Charlson comorbidity scores with age and gender matched (2:1 ratio) patients with new onset juvenile idiopathic arthritis (JIA). Trends over time for annual incidence rate per million child\u2010population (AIR) were analyzed by least square regression and survival by Kaplan\u2013Meier curves.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 40 patients with JIIM (63% female, median age 8.5\u2009years) for an average AIR of 2.52 per million (CI 1.09\u20135.57). AIR was stable over time leading to a point prevalence of 52.61 (CI 40.57\u201367.06) in 2015. Most patients (80%) were classified as JDM with an AIR for JDM of 2.02 (CI 1.09\u20135.58) and AIR for the combined other JIIM at 0.51 (CI 0.24\u20131.15). There was female preponderance (62.5%) in both JIIM groups, but no evidence of seasonality. Over a median follow\u2010up of 13\u2009years, one\u2010 and ten\u2010year survival was 94.1%. Compared to JIA patients, readmission (80.4 vs. 63.7, <jats:italic>p<\/jats:italic>\u2009=\u2009.02) and infection rates (15.2 vs. 9.6, <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.01) per 100 person\u2010years were higher for JIIM, with similar frequency of interstitial lung disease, fractures, and thrombotic events. At last observation, nearly all patients in both JIIM cohorts (97.5 vs. 92.5%) had accrued some form of comorbidity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The overall incidence of JIIM leading to hospitalization in WA was stable over 30\u2009years. JIIM prognosis remains suboptimal due to early mortality and accrual of long\u2010term comorbidity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.15379","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T07:06:03Z","timestamp":1729235163000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Incidence and outcomes for children with idiopathic inflammatory myopathy in Western Australia\u2014a long\u2010term population\u2010based study"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2833-7997","authenticated-orcid":false,"given":"Johannes","family":"Nossent","sequence":"first","affiliation":[{"name":"Department of Rheumatology Sir Charles Gairdner Hospital  Perth Western Australia Australia"},{"name":"Rheumatology Group, School of Medicine University Western Australia  Perth Western Australia 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