{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T11:52:42Z","timestamp":1789645962558,"version":"4.0.0"},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T00:00:00Z","timestamp":1739491200000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100020830","name":"AYUMI Pharmaceutical","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020830","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010740","name":"Asahi Kasei Pharma Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010740","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J of Rheum Dis"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This longitudinal study investigated the factors associated with hallux valgus (HV) progression in patients with rheumatoid arthritis (RA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included 316 patients with RA who underwent foot radiography in 2015 and more than four years later. The HV angle (HVA), first\u2010second intermetatarsal angle (IMA), first\u2010fifth intermetatarsal angle (M1\/M5 angle), and calcaneal pitch (CP) angle were measured. Sesamoid position on a non\u2010weight\u2010bearing radiograph was divided into seven grades with reference to the Hardy classification. Factors of HV progression were examined.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During a mean follow\u2010up period of 6.1\u2009years, HVA increased significantly. According to the grade of the sesamoid position, feet classified as grade VI or VII showed a greater change in HVA than those classified as below grade V. In feet below grade V, high disease activity, M1\/M5 angle and right side were associated with the yearly increase &gt;\u20091\u00b0 in the HVA. For grades VI and VII, a large CP angle was correlated with greater annual changes in the HVA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Sesamoid position relates with the increase in HVA in patients with RA. Disease activity, the existence of splay foot, and the right side are significant risk factors for an HVA increase in grades I to V.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1756-185x.70131","type":"journal-article","created":{"date-parts":[[2025,2,15]],"date-time":"2025-02-15T07:29:01Z","timestamp":1739604541000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Factors Associated With Hallux Valgus Progression in Patients With Rheumatoid Arthritis: Insights From Non\u2010Weight\u2010Bearing Radiographs in the <scp>KURAMA<\/scp> Cohort"],"prefix":"10.1111","volume":"28","author":[{"given":"Tatsuhito","family":"Ikezaki","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7896-3937","authenticated-orcid":false,"given":"Koichi","family":"Murata","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kyoto University Graduate School of Medicine  Kyoto Japan"},{"name":"Department of Advanced Medicine for Rheumatic Diseases Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6556-1226","authenticated-orcid":false,"given":"Takayuki","family":"Fujii","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kyoto University Graduate School of Medicine  Kyoto Japan"},{"name":"Department of Advanced Medicine for Rheumatic Diseases Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Onishi","sequence":"additional","affiliation":[{"name":"Department of Advanced Medicine for Rheumatic Diseases Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5981-4648","authenticated-orcid":false,"given":"Kosaku","family":"Murakami","sequence":"additional","affiliation":[{"name":"Division of Clinical Immunology and Cancer Immunotherapy, Center for Cancer Immunotherapy and Immunobiology Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masao","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Advanced Medicine for Rheumatic Diseases Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Morinobu","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuichi","family":"Matsuda","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kyoto University Graduate School of Medicine  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,2,14]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.33506"},{"key":"e_1_2_11_3_1","first-page":"48","article-title":"Is it Possible to Predict Radiological Damage in Early Rheumatoid Arthritis (RA)? 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