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However, there is a lack of comprehensive nationwide data on RA prevalence, incidence, and associated economic burdens based on large\u2010scale population studies in China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A population\u2010based study was conducted based on data from the Urban Employee Basic Medical Insurance and Urban Resident Basic Medical Insurance claims covering 380 million residents from 23 provinces in China, from 2013 to 2017. The prevalence and incidence rates of RA stratified by sex, age, and region were estimated by a two\u2010stage approach with Poisson regression models. The rates were age\u2010 and sex\u2010standardized. The associated annual costs and hospital visit times were estimated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>789\u2009583 patients were identified with a mean age of 54.74\u2009\u00b1\u200914.72\u2009years, of whom 61.25% were female. The standardized prevalence rate of RA in China in 2017 was 334.35 (95% CI 288.20\u2013383.92) per 100\u2009000 people with 443.97 (95% CI 368.23\u2013526.76) and 242.25 (95% CI 188.87\u2013302.24) per 100\u2009000 people in females and males. The prevalence increased at an average annual rate of 21.79%. The incidence rate in 2017 was 128.71 (95% CI, 101.69\u2013158.91) per 100\u2009000 person\u2010years. The prevalence and incidence rates peaked at 65\u201374\u2009years old in both sexes. The prevalence and incidence rates were lower in Southern China compared to other regions. The average annual cost per capita for RA patients was estimated to be US$907.78.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The high and rising prevalence, incidence, and medical costs of RA impose a substantial societal burden. Distinct patterns in prevalence across geographic regions require further research for underlying causes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1756-185x.70184","type":"journal-article","created":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T00:46:18Z","timestamp":1747356378000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prevalence and Incidence of Rheumatoid Arthritis in Urban China: A National Population\u2010Based Study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8287-324X","authenticated-orcid":false,"given":"Mengzhuo","family":"Cao","sequence":"first","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College  Beijing China"},{"name":"National Clinical Research Center for Dermatologic and Immunologic Diseases 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