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In this way, the production of cobalamin reinforces numerous microbial interdependencies. Here we report the accumulation of an unusual form of cobalamin, nitrocobalamin (NO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010cobalamin), in a marine oxygen deficient zone (ODZ), isolates of ammonia\u2010oxidizing archaea (AOA), and an anaerobic ammonium\u2010oxidizing (anammox) bacteria enriched bioreactor. Low oxygen waters were enriched in NO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010cobalamin, and AOA isolates experiencing ammonia or copper stress produced more NO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010cobalamin, though there is wide strain\u2010to\u2010strain and batch\u2010to\u2010batch variability. NO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010cobalamin has no known biochemical role. We hypothesize that AOA and anammox bacteria are a source of marine NO\n                    <jats:sub>2<\/jats:sub>\n                    \u2010cobalamin in the environment via a reactive nitrogen intermediate. These findings suggest connections between cobalamin forms and nitrogen transformations, physiological stress and ocean deoxygenation.\n                  <\/jats:p>","DOI":"10.1111\/1758-2229.12664","type":"journal-article","created":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T04:59:26Z","timestamp":1531976366000},"page":"453-457","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Accumulation of NO\n                    <sub>2<\/sub>\n                    \u2010cobalamin in nutrient\u2010stressed ammonia\u2010oxidizing archaea and in the oxygen deficient zone of the eastern tropical North Pacific"],"prefix":"10.1111","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4504-1039","authenticated-orcid":false,"given":"Katherine R.","family":"Heal","sequence":"first","affiliation":[{"name":"School of Oceanography, University of Washington  Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Qin","sequence":"additional","affiliation":[{"name":"School of Oceanography, University of Washington  Seattle WA USA"},{"name":"Department of Civil and Environmental Engineering University of Washington  Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3780-8102","authenticated-orcid":false,"given":"Shady A.","family":"Amin","sequence":"additional","affiliation":[{"name":"Biology Division New York University Abu Dhabi  Abu Dhabi United Arab Emirates"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allan H.","family":"Devol","sequence":"additional","affiliation":[{"name":"School of Oceanography, University of Washington  Seattle WA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James W.","family":"Moffett","sequence":"additional","affiliation":[{"name":"Department of Biological Sciences University of Southern California  Los Angeles CA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. 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