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Disease aetiology can involve\n                    <jats:italic>Legionella<\/jats:italic>\n                    replication intracellularly within protists and this study aimed to characterise the\n                    <jats:italic>Legionella<\/jats:italic>\n                    \u2010protist relationship to develop novel outbreak prevention targets. Water and sediment samples were collected from a water\u2010cooling tower in South Carolina over a 6\u2010month period. Concomitantly, multiple environmental parameters were recorded. Bacterial and eukaryotic communities were characterised using 16S rRNA gene V4 region and a 252\u2009bp fragment of 18S rRNA gene, respectively. Co\u2010occurrence network analyses were performed to elucidate\n                    <jats:italic>Legionella<\/jats:italic>\n                    \u2010protist correlations through time. We found that\n                    <jats:italic>Legionella<\/jats:italic>\n                    correlated with different protists as the seasons progressed.\n                    <jats:italic>Acanthamoeba<\/jats:italic>\n                    correlated with\n                    <jats:italic>Legionella<\/jats:italic>\n                    in early spring followed by\n                    <jats:italic>Vannella<\/jats:italic>\n                    and\n                    <jats:italic>Korotnevella<\/jats:italic>\n                    in late spring and early summer, and were joined by\n                    <jats:italic>Echinamoeba<\/jats:italic>\n                    in mid\u2010summer.\n                    <jats:italic>Vannella<\/jats:italic>\n                    and\n                    <jats:italic>Acanthamoeba<\/jats:italic>\n                    are known potential hosts for\n                    <jats:italic>Legionella<\/jats:italic>\n                    , while\n                    <jats:italic>Korotnevella<\/jats:italic>\n                    is a potential undocumented host. Of the environmental parameters, temperature showed strong correlation with protists genera, suggesting that\n                    <jats:italic>Legionella<\/jats:italic>\n                    abundance was driven by temperature\u2010dependent protist availability. Our results highlight ecological shifts that are associated with elevated\n                    <jats:italic>Legionella<\/jats:italic>\n                    levels, which offers potential targets to help predict and prevent disease outbreaks.\n                  <\/jats:p>","DOI":"10.1111\/1758-2229.70132","type":"journal-article","created":{"date-parts":[[2025,6,30]],"date-time":"2025-06-30T03:21:11Z","timestamp":1751253671000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Seasonal Host Shifts for\n                    <i>Legionella<\/i>\n                    Within an Industrial Water\u2010Cooling System"],"prefix":"10.1111","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9516-0119","authenticated-orcid":false,"given":"Suzanne","family":"Crull","sequence":"first","affiliation":[{"name":"Department of Biological Sciences Clemson University  Clemson South Carolina 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