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A mixture of four phages able to infect strains of\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                    <\/jats:styled-content>\n                    ,\n                    <jats:italic>Enterobacter<\/jats:italic>\n                    sp. and\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                    <\/jats:styled-content>\n                    was tested on three\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>D. magna<\/jats:italic>\n                    <\/jats:styled-content>\n                    clones\n                    <jats:italic>.<\/jats:italic>\n                    The host\u2010associated microbiome composition in both the examined variants and the control was analysed using 16S rRNA amplicon sequencing. Additionally, the survival, growth rate, age, size at the first reproduction, and neonate per female were assessed. The analysis revealed minor shifts in microbial composition following phage exposure. Nevertheless, results showed that the phage cocktail increased microbiome diversity. None of the life\u2010history parameters studied were affected by the presence of the phage cocktail, and no adverse effects were observed. The results indicated that under laboratory conditions the phage cocktail is safe for\n                    <jats:styled-content style=\"fixed-case\">\n                      <jats:italic>D. magna<\/jats:italic>\n                    <\/jats:styled-content>\n                    and its microbiome.\n                  <\/jats:p>","DOI":"10.1111\/1758-2229.70329","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T10:44:11Z","timestamp":1775645051000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Phage Cocktail Designed for Wastewater Bioremediation Has Limited Effect on Crustacean Filtrator Microbiome Diversity and Health"],"prefix":"10.1111","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-9781-7831","authenticated-orcid":false,"given":"Marta","family":"Grabska","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Microbiology Institute of Biology, Warsaw University of Life Sciences (WULS)  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4028-8136","authenticated-orcid":false,"given":"Adrian","family":"Gorecki","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Microbiology Institute of Biology, Warsaw University of Life Sciences (WULS)  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4323-7564","authenticated-orcid":false,"given":"Hannah V.","family":"Pye","sequence":"additional","affiliation":[{"name":"Quadram Institute Bioscience, Norwich Research Park  Norwich UK"},{"name":"Centre for Microbial Interactions Norwich Research Park  Norwich UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4826-5406","authenticated-orcid":false,"given":"Evelien M.","family":"Adriaenssens","sequence":"additional","affiliation":[{"name":"Quadram Institute Bioscience, Norwich Research Park  Norwich UK"},{"name":"Centre for Microbial Interactions Norwich Research Park  Norwich UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9331-7183","authenticated-orcid":false,"given":"Malgorzata","family":"Grzesiuk","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Microbiology Institute of Biology, Warsaw University of Life Sciences (WULS)  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1159\/000334691"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2019.135827"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2021.152093"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0801925105"},{"key":"e_1_2_11_6_1","unstructured":"Andrews S.2010.\u201cFastQC: A Quality Control Tool for High Throughput Sequence Data.\u201dhttp:\/\/www.bioinformatics.babraham.ac.uk\/projects\/fastqc."},{"key":"e_1_2_11_7_1","unstructured":"Bischoff H. 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