{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T05:06:17Z","timestamp":1770440777827,"version":"3.49.0"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,6,5]],"date-time":"2015-06-05T00:00:00Z","timestamp":1433462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Post\u2010pneumonectomy syndrome (<jats:styled-content style=\"fixed-case\">PPS<\/jats:styled-content>) is a rare syndrome characterized by trachea\u2010bronchial stenosis and severe dyspnea. In this study, we retrospectively evaluated the clinical outcomes in patients who underwent placement of tissue expanders for <jats:styled-content style=\"fixed-case\">PPS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from patients who underwent placement of tissue expanders for <jats:styled-content style=\"fixed-case\">PPS<\/jats:styled-content> were analyzed for preoperative characteristics, surgical techniques, and postoperative outcomes. Between 1997 and 2014, a total of 10 patients were treated for <jats:styled-content style=\"fixed-case\">PPS<\/jats:styled-content> by tissue expanders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age of the 10 patients was 45 years (range, 16\u201370). Four patients had undergone right pneumonectomy, three patients had undergone left pneumonectomy, and three patients had post\u2010pneumonectomy\u2010like syndrome. Preoperatively, seven patients initially received high oxygen therapy for hypoxemia but progressed to respiratory failure, and three patients required mechanical ventilator support. Among these three patients, one required intraoperative extracorporeal membrane oxygenation support because of sudden cardiac arrest during preparation for surgery. The median follow\u2010up was 59.5 months (range, 2\u2013204). The median interval between pneumonectomy and repositioning was 13 months (range, 8\u2013581). Two patients underwent placement of a single tissue expander, and two tissue expanders were placed in eight of the 10 patients. The median volume of tissue expanders inflated with saline was 450\u2009cc (range, 60\u2013850\u2009cc) per tissue expander. There was no perioperative mortality in our study. Complications occurred in four patients (40%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Repositioning of the mediastinum with placement of a saline filled tissue expander for <jats:styled-content style=\"fixed-case\">PPS<\/jats:styled-content> is very effective for the relief of symptoms, with low mortality.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.12282","type":"journal-article","created":{"date-parts":[[2015,6,5]],"date-time":"2015-06-05T07:44:15Z","timestamp":1433490255000},"page":"88-93","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Management of post\u2010pneumonectomy syndrome using tissue expanders"],"prefix":"10.1111","volume":"7","author":[{"given":"Jae Jun","family":"Jung","sequence":"first","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jong Ho","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong Kwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Soo","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jhingook","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae Ill","family":"Zo","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Mog","family":"Shim","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery Samsung Medical Center Sungkyunkwan University School of Medicine  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,5]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"551","volume-title":"General Thoracic Surgery","author":"Haithcock BE","year":"2009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.11.022"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.05.014"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(00)02404-8"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0218492314534252"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.12.035"},{"key":"e_1_2_7_8_1","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/S0022-5223(19)41864-3","article-title":"Severe airway obstruction caused by mediastinal displacement after right pneumonectomy in a child. 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