{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T17:54:15Z","timestamp":1783619655835,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T00:00:00Z","timestamp":1478563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2017,3]]},"abstract":"Small cell lung cancer (SCLC<\/jats:styled-content>) is a neuroendocrine tumor with the potential to secrete various peptides or hormones that can lead to paraneoplastic syndromes, such as E<\/jats:styled-content>ctopic C<\/jats:styled-content>ushing syndrome (ECS<\/jats:styled-content>). Because of the aggressive nature of the syndrome and its atypical features, ECS<\/jats:styled-content> in small\u2010cell lung cancer is difficult to diagnose and has a poor prognosis. We report a case of a 74\u2010year\u2010old male patient who presented with severe hypokalemia, proximal muscle weakness, peripheral edema, metabolic alkalosis, and worsening hyperglycemia. The patient was eventually diagnosed with stage IV<\/jats:styled-content> primary small\u2010cell lung cancer and survived three\u2009months after diagnosis. We reviewed published articles to determine any new diagnostic techniques or advantages in the treatment regimen.<\/jats:p>","DOI":"10.1111\/1759-7714.12403","type":"journal-article","created":{"date-parts":[[2016,11,8]],"date-time":"2016-11-08T11:16:41Z","timestamp":1478603801000},"page":"114-117","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Ectopic C<\/scp>ushing syndrome in small cell lung cancer: A<\/scp> case report and literature review"],"prefix":"10.1111","volume":"8","author":[{"given":"Hang\u2010yu","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Interventional Therapy, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Peking University Cancer Hospital and Institute Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Thoracic Medical Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Peking University Cancer Hospital and Institute Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,11,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.01.069"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-1542"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-2527"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.5603\/EP.2015.0002"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v5.i3.197"},{"key":"e_1_2_6_7_1","first-page":"pii: bcr2013009","article-title":"Cardio\u2010respiratory failure secondary to ectopic Cushing\u2019s syndrome as the index presentation of small\u2010cell lung cancer","volume":"2013","author":"Stempel C","year":"2013","journal-title":"BMJ Case Rep"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2011.12.007"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197505)35:5<1430::AID-CNCR2820350529>3.0.CO;2-O"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.50.4127"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/659232"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11154-010-9139-z"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.4046\/trd.2015.78.4.436"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1992.10.1.21"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-927284"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.55.6139"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1985.00360050119020"}],"container-title":["Thoracic Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1759-7714.12403","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1759-7714.12403","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.12403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T23:03:36Z","timestamp":1696201416000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1759-7714.12403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,8]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1111\/1759-7714.12403"],"URL":"https:\/\/doi.org\/10.1111\/1759-7714.12403","archive":["Portico"],"relation":{},"ISSN":["1759-7706","1759-7714"],"issn-type":[{"value":"1759-7706","type":"print"},{"value":"1759-7714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,8]]},"assertion":[{"value":"2016-09-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-11-08","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}