{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:08:06Z","timestamp":1790665686583,"version":"4.1.0"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,3,15]],"date-time":"2017-03-15T00:00:00Z","timestamp":1489536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2017,5]]},"abstract":"\n Background<\/jats:title>\n \n The study was conducted to investigate clinical and computed tomography (\n CT<\/jats:styled-content>\n ) features in\n C<\/jats:styled-content>\n hinese lung cancer patients with human immunodeficiency virus (\n HIV<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Forty consecutive lung cancer patients with\n HIV<\/jats:styled-content>\n were included. Clinical data were collected, and\n CT<\/jats:styled-content>\n features were reviewed and measured. The factors associated with stages of cancer and the\n CT<\/jats:styled-content>\n features with opportunistic pulmonary infections (\n OPI<\/jats:styled-content>\n s) were also analyzed.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Thirty\u2010four of the patients were men (85%), and the mean age was 57.5\u2009years. The mean\n CD<\/jats:styled-content>\n 4 count was 288\u2009cells\/\u03bcL, and 23 patients received highly active antiretroviral therapy.\n OPIs<\/jats:styled-content>\n were common (50%). The major histological type (85%) was non\u2010small cell lung cancer (\n NSCLC<\/jats:styled-content>\n ), and 15\n NSCLC<\/jats:styled-content>\n patients (44%) were in stages\n III<\/jats:styled-content>\n b and\n IV<\/jats:styled-content>\n .\n NSCLC<\/jats:styled-content>\n patients with an\n OPI<\/jats:styled-content>\n were more common in the advanced stages compared with those without an\n OPI<\/jats:styled-content>\n (\n P<\/jats:italic>\n \u2009=\u20090.04). There were no significant differences in advanced and non\u2010advanced stages in terms of\n CD<\/jats:styled-content>\n 4 level, highly active antiretroviral therapy, and smoking (\n P<\/jats:italic>\n \u2009=\u20090.31,\n P<\/jats:italic>\n \u2009=\u20091.00;\n P<\/jats:italic>\n \u2009=\u20090.49, respectively). The average size of tumors was 4.5\u2009cm. Irregularly shaped or larger sized tumors were associated with\n OPI<\/jats:styled-content>\n s (\n P<\/jats:italic>\n \u2009=\u20090.03,\n P<\/jats:italic>\n \u2009=\u20090.04, respectively).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n The persistence of locally irregular and large lesions in middle\u2010aged men with\n HIV<\/jats:styled-content>\n and a history of\n OPI<\/jats:styled-content>\n s should be an alert for lung cancer, and clinical management is needed.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/1759-7714.12429","type":"journal-article","created":{"date-parts":[[2017,3,15]],"date-time":"2017-03-15T04:24:08Z","timestamp":1489551848000},"page":"238-245","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical and computed tomography findings in\n C<\/scp>\n hinese lung cancer patients with\n HIV<\/scp>\n infection:\n A<\/scp>\n multi\u2010center study"],"prefix":"10.1111","volume":"8","author":[{"given":"Zenghui","family":"Cheng","sequence":"first","affiliation":[{"name":"Department of Radiology, Shanghai Public Health Clinical Center Fudan University Shanghai China"},{"name":"Department of Radiology Qingpu Branch of Zhongshan Hospital, Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Radiology, Shanghai Public Health Clinical Center Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinxin","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Radiology Guangzhou Eighth People's Hospital Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxin","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Shanghai Public Health Clinical Center Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Radiology, Shanghai Public Health Clinical Center Fudan University Shanghai China"},{"name":"Headmaster's Office Fudan University Shanghai China"},{"name":"Department of Radiology Zhongshan Hospital, Fudan University Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guowei","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Radiology Guangxi Longtan Hospital Liuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13802-0"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000233310.90484.16"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29603"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25530"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-011-0085-5"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.19.6626"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3282f47082"},{"key":"e_1_2_7_9_1","first-page":"226","article-title":"The spectrum of malignancies among adult HIV cohort in Poland between 1995 and 2012: A retrospective analysis of 288 cases","volume":"19","author":"Kowalski J","year":"2015","journal-title":"Contemp Oncol (Pozn)"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-148-10-200805200-00005"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1997.02805.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e3181b327ca"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.13.1736"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-1699"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.5501\/wjv.v4.i3.209"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/1758-2652-13-51"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181f387fd"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-016-1416-3"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000232260.95288.93"},{"key":"e_1_2_7_20_1","unstructured":"UNAIDS.2014 China AIDS Response Progress Report. 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