{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T01:52:12Z","timestamp":1767837132607,"version":"3.49.0"},"reference-count":35,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,10,4]],"date-time":"2017-10-04T00:00:00Z","timestamp":1507075200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005088","name":"Beijing Municipal Bureau of Health","doi-asserted-by":"publisher","award":["2015\u20103\u2010057"],"award-info":[{"award-number":["2015\u20103\u2010057"]}],"id":[{"id":"10.13039\/501100005088","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Esophageal cancer (EC) is ranked as the top 10th malignancy in China; however, an association between peanut consumption and EC risk has not yet been identified. This study explored the protective effects of peanut consumption against the risk of developing esophageal squamous cell carcinoma (ESCC) in a high\u2010risk area.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A case\u2013control design was applied, with frequency matching by age and gender. A logistic regression model was used to estimate odds ratios (OR) and 95% confidence intervals (CI). Two hundred and twenty\u2010two cases and 222 controls were recruited from Yanting County from 2011 to 2012.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Peanut consumption 1\u20133 times per week reduced cancer risk by 38% (OR\u20090.62, 95% CI 0.34\u20131.13), while consumption \u2265 4 times per week reduced the risk by 70% (OR\u20090.31, 95% CI 0.16\u20130.59). A significant association was observed among individuals with negative family EC history (OR\u20090.25, 95% CI 0.12\u20130.49).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Peanut consumption may act as a protector against the occurrence of ESCC in high\u2010risk areas, thus production and consumption should be promoted in high\u2010risk areas in order to reduce the ESCC burden.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.12520","type":"journal-article","created":{"date-parts":[[2017,10,4]],"date-time":"2017-10-04T12:22:37Z","timestamp":1507119757000},"page":"30-36","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Peanut consumption associated with a reduced risk of esophageal squamous cell carcinoma: <scp>A<\/scp> case\u2013control study in a high\u2010risk area in <scp>C<\/scp>hina"],"prefix":"10.1111","volume":"9","author":[{"given":"Yanjie","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, Beijing Shijitan Hospital Capital Medical University, The Ninth Academic Hospital of Peking University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Medical Records and Statistics, Xuanwu Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiping","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery Peking University People's Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangping","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Beijing Shijitan Hospital Capital Medical University, The Ninth Academic Hospital of Peking University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Cancer Early Detection and Treatment Yanting Cancer Hospital  Mianyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenxu","family":"Qu","sequence":"additional","affiliation":[{"name":"USC Norris Comprehensive Cancer Center  Los Angeles California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongming","family":"He","sequence":"additional","affiliation":[{"name":"Department of Cancer Early Detection and Treatment Yanting Cancer Hospital  Mianyang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1159-257X","authenticated-orcid":false,"given":"Qingkun","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Science of Technology, Beijing Shijitan Hospital Capital Medical 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