{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:41:49Z","timestamp":1781052109759,"version":"3.54.1"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2019,6,11]],"date-time":"2019-06-11T00:00:00Z","timestamp":1560211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>A 32\u2010year\u2010old woman was referred to our hospital because of severe psychosis and was found to have an ectopic ACTH\u2010producing thymic neuroendocrine tumor. Laboratory data revealed an elevated serum cortisol and plasma ACTH level, hypokalemia, and metabolic alkalosis. Chest computed tomography (CT) revealed an anterior mediastinal mass and multiple pulmonary nodules. As the patient was unable to communicate because of her consciousness disturbance, she was managed with artificial ventilation and deep sedation. Metyrapone and potassium supplementation were administered, and steroid psychosis gradually improved. Thoracic surgery was performed and the histopathological diagnosis was thymic neuroendocrine tumor with positive anti\u2010ACTH immunohistochemical staining. Here we present details of the case and review the literature.<\/jats:p>","DOI":"10.1111\/1759-7714.13099","type":"journal-article","created":{"date-parts":[[2019,6,12]],"date-time":"2019-06-12T04:28:48Z","timestamp":1560313728000},"page":"1648-1653","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["ACTH\u2010producing thymic neuroendocrine tumor initially presenting as psychosis: A case report and literature review"],"prefix":"10.1111","volume":"10","author":[{"given":"Taiki","family":"Okumura","sequence":"first","affiliation":[{"name":"Second Department of Internal Medicine Shinshu University School of Medicine  Asahi Matsumoto Japan"},{"name":"Department of Comprehensive Cancer Therapy Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shohei","family":"Takayama","sequence":"additional","affiliation":[{"name":"Fourth Department of Internal Medicine Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin\u2010ichi","family":"Nishio","sequence":"additional","affiliation":[{"name":"Fourth Department of Internal Medicine Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Miyakoshi","sequence":"additional","affiliation":[{"name":"Fourth Department of Internal Medicine Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuro","family":"Noguchi","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Cancer Therapy Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Cancer Therapy Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshirou","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Cancer Therapy Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nodoka","family":"Sekiguchi","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Cancer Therapy Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiaki","family":"Otsuki","sequence":"additional","affiliation":[{"name":"Department of Central Laboratory Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsuhisa","family":"Komatsu","sequence":"additional","affiliation":[{"name":"Fourth Department of Internal Medicine Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5182-0960","authenticated-orcid":false,"given":"Tomonobu","family":"Koizumi","sequence":"additional","affiliation":[{"name":"Department of Comprehensive Cancer Therapy Shinshu University School of Medicine  Asahi Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,11]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-15-0968"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000340"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-16-0809"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-2527"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1744-859X-12-23"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thorsurg.2010.08.013"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(02)03547-6"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-3355"},{"key":"e_1_2_5_10_1","first-page":"246","article-title":"Carcinoid tumor of the thymus. 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