{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:36:04Z","timestamp":1793093764938,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T00:00:00Z","timestamp":1562630400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["GG201809240204"],"award-info":[{"award-number":["GG201809240204"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>To evaluate the efficacy and safety of artificial pneumothorax with position adjustment for computed tomograpy (CT)\u2010guided percutaneous transthoracic microwave ablation (MWA) of small subpleural lung tumors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010six patients with small subpleural lung tumors (&lt; 3.0 cm) entered the study and underwent CT\u2010guided MWA with (group I: 24 patients with 24 tumors) or without (group II: 32 patients with 34 tumors) the support of artificial pneumothorax. Follow\u2010up contrast\u2010enhanced CT scans were reviewed. Pain VAS (visual analog scale) scores at, during, and after ablation were compared between the two groups. Technical success, technique efficacy, local tumor control and complications were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Creation of the artificial pneumothorax was achieved for 24\/24 (100%) in group I and no complication related to the procedure was observed. Technical success of MWA was achieved for all 58 tumors. Primary efficacy of MWA was achieved in 23 of 24 tumors (95.8%) treated in group I, and 32 of 34 tumors (94.1%) treated in group II (<jats:italic>P<\/jats:italic> = 0.771). The 12\u2010month local tumor control was achieved in 87.5% (21\/24) in group I compared with 88.2% (30\/34) in group II (<jats:italic>P<\/jats:italic> = 0.833). Pain VAS scores in group I were significantly decreased after the pneumothorax induction at, during, and after ablation compared with group II (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05). There was no significant difference in MWA\u2010related complications (<jats:italic>P<\/jats:italic>\u2009&gt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Artificial pneumothorax with position adjustment for CT\u2010guided MWA is effective and may be safely applied to small subpleural lung tumors. Artificial pneumothorax is a reliable therapy for pain relief.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.13137","type":"journal-article","created":{"date-parts":[[2019,7,10]],"date-time":"2019-07-10T04:49:38Z","timestamp":1562734178000},"page":"1710-1716","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Efficacy and safety of artificial pneumothorax with position adjustment for CT\u2010guided percutaneous transthoracic microwave ablation of small subpleural lung tumors"],"prefix":"10.1111","volume":"10","author":[{"given":"Haipeng","family":"Jia","sequence":"first","affiliation":[{"name":"Department of Radiology Qilu Hospital of Shandong University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Tian","sequence":"additional","affiliation":[{"name":"Department of Respiration Huantai County Hospital of Traditional Chinese Medicine  Zibo 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