{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T06:37:10Z","timestamp":1772951830363,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,8,21]],"date-time":"2019-08-21T00:00:00Z","timestamp":1566345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>Here, we report a case of myasthenia gravis and myopathy in a patient treated with nivolumab. A 76\u2010year\u2010old man who had been treated with four doses of nivolumab because of non\u2010small cell lung cancer (NSCLC) presented with proximal\u2010dominant muscle weakness and fluctuating ptosis and diplopia. Serologic studies revealed increased levels of muscle enzymes including creatine phosphokinase (2934 U\/L), and acetylcholine receptor antibody was positive (1.31 nmol\/L). Following electrodiagnostic study, he was diagnosed with myasthenia gravis and active stage of myopathy. After discontinuation of nivolumab, he was treated with corticosteroids, intravenous immunoglobulin G, and pyridostigmine. The neuromuscular symptoms and serologic abnormalities of the patient markedly improved. Currently, he is taking oral steroids and pyridostigmine without further immunotherapy.<\/jats:p>","DOI":"10.1111\/1759-7714.13177","type":"journal-article","created":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T02:53:01Z","timestamp":1566442381000},"page":"2045-2049","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Myasthenia gravis and myopathy after nivolumab treatment for non\u2010small cell lung carcinoma: A case report"],"prefix":"10.1111","volume":"10","author":[{"given":"Je\u2010Seong","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Chonnam National University Medical School, and Chonnam National University Hwasun Hospital  Hwasun South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tai\u2010Seung","family":"Nam","sequence":"additional","affiliation":[{"name":"Department of Neurology Chonnam National University Medical School and Chonnam National University Hospital  Gwangju South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jieun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chonnam National University Medical School, and Chonnam National University Hwasun Hospital  Hwasun South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo\u2010Gun","family":"Kho","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chonnam National University Medical School, and Chonnam National University Hwasun Hospital  Hwasun South Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheol\u2010Kyu","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Chonnam National University Medical School, and Chonnam National University Hwasun Hospital  Hwasun South 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