{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:53:56Z","timestamp":1791420836434,"version":"4.3.3"},"reference-count":13,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T00:00:00Z","timestamp":1590019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:p>Liposarcoma is a malignant adipose tissue tumor which mainly originates from the extremities and retroperitoneum. Primary pleural liposarcoma is very rare. Spindle cell lipoma is a rare benign adipose tissue tumor. A 66\u2010year\u2010old male was referred to our hospital for the evaluation of a mass\u2010like opacity visible on chest X\u2010ray. Computed tomography (CT) scan revealed a well\u2010defined soft tissue mass with internal low attenuations and adjacent multiple nodules in the upper lobe of the left lung, and surgical excision was subsequently performed. Histopathological findings revealed adipose tissue with lipoblasts and spindle cells and immunohistochemical staining (IHC) revealed the tumor cells were strongly positive for CDK4 and MDM2. Histopathological examination of the small lung nodules showed spindle cell proliferation and adipose tissue without positivity for MDM2. Here, we report a rare case of primary pleural liposarcoma combined adjacent spindle cell lipoma of the lung.<\/jats:p>","DOI":"10.1111\/1759-7714.13495","type":"journal-article","created":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T22:42:32Z","timestamp":1590100952000},"page":"2059-2062","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Primary pleural liposarcoma combined spindle cell lipoma of the lung"],"prefix":"10.1111","volume":"11","author":[{"given":"Lae Hyung","family":"Kang","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, School of Medicine Pusan National University  Yangsan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung Su","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Pathology, School of Medicine Pusan National University  Yangsan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2075-4702","authenticated-orcid":false,"given":"Seong Hoon","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, School of Medicine Pusan National University  Yangsan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,5,21]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.12771"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197511)36:5<1852::AID-CNCR2820360542>3.0.CO;2-U"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1749-8090-9-119"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0720-048X(00)00168-6"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cancergencyto.2007.09.006"},{"issue":"9","key":"e_1_2_5_7_1","first-page":"E166","article-title":"Primary pleural liposarcoma, pleomorphic variant","volume":"6","author":"Carrillo BJA","year":"2014","journal-title":"J Thorac Dis"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e31819e77ff"},{"issue":"5","key":"e_1_2_5_9_1","doi-asserted-by":"crossref","first-page":"699","DOI":"10.5858\/2000-124-0699-LOTPC","article-title":"Liposarcoma of the pleural cavity: Clinical and pathologic features of 4 cases with a review of the literature","volume":"124","author":"Okby NT","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200205000-00006"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-0584"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqw137"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.181.5.1811251"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000770"}],"container-title":["Thoracic Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2F1759-7714.13495","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.13495","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1759-7714.13495","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.13495","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T13:57:47Z","timestamp":1693922267000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1759-7714.13495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,21]]},"references-count":13,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1111\/1759-7714.13495"],"URL":"https:\/\/doi.org\/10.1111\/1759-7714.13495","archive":["Portico"],"relation":{},"ISSN":["1759-7706","1759-7714"],"issn-type":[{"value":"1759-7706","type":"print"},{"value":"1759-7714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,21]]},"assertion":[{"value":"2020-04-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}