{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T17:02:25Z","timestamp":1784739745610,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T00:00:00Z","timestamp":1599436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:p>Malignant tumors are often associated with eosinophilic pleural effusion. Here, we encountered a case of interleukin\u20105 (IL\u20105)\u2010producing malignant pleural mesothelioma with eosinophilic pleural effusion. The patient was a 50\u2010year\u2010old male. He had a history of a cough for several weeks and had visited a local doctor. Left pleural effusion was noted, and the patient was referred to our hospital. He was diagnosed with malignant pleural mesothelioma by pleural biopsy, with eosinophilic pleural effusion. IL\u20105 in the pleural effusion increased, and tumor cells were IL\u20105\u2010positive by immunostaining. There have been few reports of IL\u20105\u2010producing tumors, and this is the first report of IL\u20105\u2010producing malignant pleural mesothelioma. Host\u2010tumor cell interactions cause eosinophilic pleural effusion. In patients with eosinophilic pleural effusion, malignant pleural effusion should be considered. It is necessary to clarify the pathophysiology of malignant tumors and eosinophils.<\/jats:p>","DOI":"10.1111\/1759-7714.13652","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T20:08:42Z","timestamp":1601323722000},"page":"3043-3046","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Interleukin\u20105\u2010producing malignant pleural mesothelioma with eosinophilic pleural effusion"],"prefix":"10.1111","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1541-9747","authenticated-orcid":false,"given":"Eiji","family":"Takeuchi","sequence":"first","affiliation":[{"name":"Department of Clinical Investigation National Hospital Organization Kochi Hospital  Kochi Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine and Rheumatology Tokushima 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