{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T22:36:12Z","timestamp":1773009372605,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T00:00:00Z","timestamp":1620950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Small cell lung cancer (SCLC) is an aggressive malignancy with a poor prognosis that accounts for 10% of all cases of clinical lung cancer. Due to its high growth fraction and rapid doubling time it is usually diagnosed as extensive local or metastatic disease in 60%\u201370% of cases. Combined small cell lung cancer (C\u2010SCLC) is a relatively rare subtype of SCLC and is defined as SCLC combined with any elements of non\u2010small cell lung cancer (NSCLC). Clinical presentation of SCLC as an isolated pedunculated endotracheal lesion is an especially rare occurrence. Here, we report for the first time the occurrence of a C\u2010SCLC as a polypoid tumor of the trachea diagnosed in an 80\u2010year\u2010old woman admitted to the emergency department with a principal complaint of cough and wheezing.<\/jats:p>","DOI":"10.1111\/1759-7714.13992","type":"journal-article","created":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T21:39:38Z","timestamp":1621028378000},"page":"2035-2038","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Tracheal polypoid <scp>combined small cell lung cancer (C\u2010SCLC)<\/scp>: A case report"],"prefix":"10.1111","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3032-9494","authenticated-orcid":false,"given":"Alberto","family":"Testori","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Humanitas Research Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Ferraroli","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Humanitas Research Hospital  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camilla","family":"De Carlo","sequence":"additional","affiliation":[{"name":"Department of Pathology Humanitas Clinical and Research Center \u2013 IRCCS  Rozzano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Bossi","sequence":"additional","affiliation":[{"name":"Department of Pathology Humanitas Clinical and Research Center \u2013 IRCCS  Rozzano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Alloisio","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Humanitas Research Hospital  Milan Italy"},{"name":"Department of Biomedical Sciences Humanitas University  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8394-2719","authenticated-orcid":false,"given":"Giuseppe","family":"Mangiameli","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery IRCCS Humanitas Research Hospital  Milan Italy"},{"name":"Department of Biomedical Sciences Humanitas University  Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,14]]},"reference":[{"issue":"1","key":"e_1_2_5_2_1","first-page":"39","article-title":"Small cell lung cancer (SCLC): no treatment advances in recent years","volume":"5","author":"Koinis F","year":"2016","journal-title":"Transl Lung Cancer Res."},{"key":"e_1_2_5_3_1","volume-title":"WHO classification of tumours of the lung, pleura, thymus and heart","author":"Travis WD","year":"2015"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-200607000-00017"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-013-0428-1"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2005.09.016"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S159057"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.13591"},{"key":"e_1_2_5_9_1","first-page":"101","article-title":"A rare case of multiple secondary endotracheal metastasis from early stage small cell cancer","volume":"30","author":"Karakattu S","year":"2020","journal-title":"Respir Med Case Rep."},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0b013e31824dd182"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/97077007"},{"key":"e_1_2_5_12_1","first-page":"99","article-title":"Primary carcinoma of the trachea: combined small cell, squamous cell and giant cell carcinoma. Report of a case and review of the literature","volume":"78","author":"Marigil MA","year":"1986","journal-title":"Pathologica"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.01.065"}],"container-title":["Thoracic Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.13992","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1759-7714.13992","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.13992","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T10:38:39Z","timestamp":1693391919000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1759-7714.13992"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,14]]},"references-count":12,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1111\/1759-7714.13992"],"URL":"https:\/\/doi.org\/10.1111\/1759-7714.13992","archive":["Portico"],"relation":{},"ISSN":["1759-7706","1759-7714"],"issn-type":[{"value":"1759-7706","type":"print"},{"value":"1759-7714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,14]]},"assertion":[{"value":"2021-03-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}