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Tumor shrinkage was observed, but asymptomatic grade 4 hypomagnesemia occurred on day 8 of the second cycle. He received magnesium replenishment and hypomagnesemia recovered on day 40, but tumor progression was observed during the period of magnesium correction. Hypomagnesemia is known as a major adverse event of treatment with anti\u2010EGFR antibodies, but there have been no case reports of severe hypomagnesemia or its clinical course.<\/jats:p>","DOI":"10.1111\/1759-7714.13999","type":"journal-article","created":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T01:35:17Z","timestamp":1622597717000},"page":"2039-2042","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Lung squamous cell carcinoma with severe hypomagnesemia due to cisplatin plus gemcitabine in combination with necitumumab therapy: A case report"],"prefix":"10.1111","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8308-4227","authenticated-orcid":false,"given":"Akira","family":"Nakao","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine Fukuoka University Hospital  Fukuoka 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