{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T00:29:47Z","timestamp":1774916987215,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"23","license":[{"start":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T00:00:00Z","timestamp":1634688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>This study aimed to retrospectively explore the safety and feasibility of computed tomography (CT)\u2010guided synchronous microwave ablation (MWA) followed by core\u2010needle biopsy (CNB) via a coaxial cannula for highly suspected malignant lung ground\u2010glass opacities (GGOs).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The clinical data of 66 patients (66 GGOs) treated with CT\u2010guided synchronous MWA followed by CNB via a coaxial cannula from January 2019 to January 2021 were included in this study. The technical success rate, curative effect, and complications were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Technical success rates were 100%. The pneumothorax rate was 36.4% (24\/66). 72.7% (48\/66) patients had the bronchopulmonary hemorrhage, 81.3% of hemorrhage was attributable to CNB. 24.2% (16\/66) patients had varying degrees of pleural effusion. The pathological results were adenocarcinomas (<jats:italic>n<\/jats:italic>\u00a0=\u00a044), atypical adenomatous hyperplasia (<jats:italic>n<\/jats:italic>\u00a0=\u00a02), chronic inflammation (<jats:italic>n<\/jats:italic>\u00a0=\u00a03) and indeterminate pathological diagnosis (<jats:italic>n<\/jats:italic>\u00a0=\u00a017) with a 69.7% (46\/66) positive diagnosis rate. The therapeutic response rate was 100.0% (66\/66).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Synchronous MWA followed by CNB via a coaxial cannula has a satisfactory ablation effectiveness and an acceptable biopsy positive rate, which is an alternative treatment for highly suspected malignant GGOs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.14189","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T13:44:47Z","timestamp":1634823887000},"page":"3216-3222","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Synchronous microwave ablation followed by <scp>core\u2010needle<\/scp> biopsy via a coaxial cannula for highly suspected malignant lung <scp>ground\u2010glass<\/scp> opacities: A <scp>single\u2010center<\/scp>, <scp>single\u2010arm<\/scp> retrospective study"],"prefix":"10.1111","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2501-4620","authenticated-orcid":false,"given":"FanLei","family":"Kong","sequence":"first","affiliation":[{"name":"Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine Chinese Academy of Medicine Sciences  Beijing China"},{"name":"Graduate School of Peking Union Medical College Chinese Academy of Medical Science  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ZhiXin","family":"Bie","sequence":"additional","affiliation":[{"name":"Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine Chinese Academy of Medicine Sciences  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"YuanMing","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine Chinese Academy of Medicine Sciences  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine Chinese Academy of Medicine Sciences  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RunQi","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine Chinese Academy of Medicine Sciences  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"ChengEn","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine Chinese Academy of Medicine Sciences  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JinZhao","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine Chinese Academy of Medicine Sciences  Beijing China"},{"name":"Graduate School of Peking Union Medical College Chinese Academy of Medical Science  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheng","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine Chinese Academy of Medicine Sciences  Beijing China"},{"name":"Graduate School of Peking Union Medical College Chinese Academy of Medical Science  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3345-1313","authenticated-orcid":false,"given":"XiaoGuang","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Minimally Invasive Tumor Therapies Center, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine Chinese Academy of Medicine Sciences  Beijing China"},{"name":"Graduate School of Peking Union Medical College Chinese Academy of Medical Science  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,10,20]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"Latest global cancer data:Cancer burden rises to 19.3 million new cases and 10.0 million cancer deaths in 2020. 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