{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:42:34Z","timestamp":1787013754799,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T00:00:00Z","timestamp":1645660800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Central airway obstruction (CAO) is one of the most challenging, potentially lethal complications in malignant and benign respiratory diseases. Worsening dyspnea is also a relevant cause for reduced quality of life in such patients. Here, we present our data on the application of covered, self\u2010expanding Y\u2010carina nitinol stents due to benign and malignant diseases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We retrospectively identified 27 patients who had undergone 31 rigid bronchoscopies with implantation of covered Y\u2010carina nitinol stents over a period of 10\u2009years in order to evaluate indication, clinical course, and outcome.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Short\u2010term survival of successfully stented patients with palliative and curative treatment goal did not differ, allowing for diagnosis independent indication. With respect to overall survival, patients with endoluminal obstruction benefited most compared to patients with fistula and\/or external compression. Granulation tissue formation (61.3%) and mucus plugging (80.6%) were the most frequent complications. Material defect (6.5%) and migration (3.2%) were rare complications that could be handled by revisional rigid bronchoscopy and stent exchange in some cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Implantation of self\u2010expanding covered Y\u2010carina nitinol stents via rigid bronchoscopy is a feasible and safe treatment option for benign and malignant central airway obstruction. Especially in palliative, malignant airway stenosis, stenting might facilitate additional treatment options and optimize dyspnea and eventually quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/1759-7714.14359","type":"journal-article","created":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T07:17:31Z","timestamp":1645687051000},"page":"1040-1049","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Central airway obstruction treatment with\n                    <scp>self\u2010expanding<\/scp>\n                    covered\n                    <scp>Y\u2010carina<\/scp>\n                    nitinol stents: A single center retrospective analysis"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1644-3573","authenticated-orcid":false,"given":"Arik Bernard","family":"Schulze","sequence":"first","affiliation":[{"name":"Department of Medicine A Hematology, Oncology and Pulmonary Medicine, University Hospital Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Evers","sequence":"additional","affiliation":[{"name":"Department of Medicine A Hematology, Oncology and Pulmonary Medicine, University Hospital Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friederike Sophia","family":"Tenk","sequence":"additional","affiliation":[{"name":"Department of Medicine A Hematology, Oncology and Pulmonary Medicine, University Hospital Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Schliemann","sequence":"additional","affiliation":[{"name":"Department of Medicine A Hematology, Oncology and Pulmonary Medicine, University Hospital Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars Henning","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Medical Department IV Pulmonary Medicine and Thoracic Oncology, Klinikum Ingolstadt  Ingolstadt Germany"},{"name":"Department of Internal Medicine II University Hospital Regensburg  Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"G\u00f6rlich","sequence":"additional","affiliation":[{"name":"Institute of Biostatistics and Clinical Research Westfaelische\u2010Wilhelms University Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Mohr","sequence":"additional","affiliation":[{"name":"Department of Medicine A Hematology, Oncology and Pulmonary Medicine, University Hospital Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,2,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare-2018-001522"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11547-016-0653-2"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0000000000000250"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thorsurg.2020.04.001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.06.093"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000005612"},{"issue":"020","key":"e_1_2_7_8_1","first-page":"1","article-title":"S3\u2010guideline: prevention, diagnostics, therapy and aftercare of lung cancer","volume":"1","author":"Guideline program oncology (German Cancer Society, German Cancer Aid, AWMF)","year":"2018","journal-title":"Guidel. 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