{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T22:57:07Z","timestamp":1784761027344,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T00:00:00Z","timestamp":1650931200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Adequate tissue sampling is fundamental for establishing a definitive diagnosis, assessing prognosis and tailoring therapy. Each of the methods for obtaining tissue (e.g., endoscopic, image guidance and surgical biopsies) results in a different diagnostic yield and complication rate profile.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>Present feasibility, and assess safety and efficacy of freehand transthoracic ultrasound\u2010guided core\u2010needle biopsies (USGNB) of thoracic lesions performed by pulmonologist.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis study of ultrasound\u2010guided core\u2010needle biopsies of thoracic lesions performed at the Pulmonary Institute of Rabin Medical Center was conducted from September 2020 to October 2021. All core\u2010needle biopsies were performed under local anesthesia with guidance of Mindray TE7 2019 US system. Procedural variables including complications and pathological diagnostic yield were the primary end point. IRB 0671\u201021\u2010RMC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In total 91 biopsy procedures were analyzed in38 females and 53 males, average age 71.1\u2009years. Twenty\u2010three (25.3%) cases were lung lesions, 7 (7.7%) \u2013 mediastinal, 13 (14.3%) \u2013 chest wall, 27 (29.7%) \u2013 pleural, and 21 (23.1%) supraclavicular lesions. Average lesion size was 51.6\u2009mm, the largest in the mediastinum and the smallest in supraclavicular locations (97.7mm and 28.0\u2009mm, respectively). Overall pathological diagnostic yield was 90%, highest success in chest wall (100%) and lowest in mediastinal biopsies (71.4%). We had only one complication \u2013hemothorax resolved by chest tube drainage\u2010 accounting for only 1.1% complication rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Safety and efficacy were demonstrated in freehand US\u2010guided core\u2010needle biopsy of thoracic lesions performed by pulmonologists. We suggest thoracic ultrasound and USG\u2010CNB be part of training and clinical practice in interventional pulmonology.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.14413","type":"journal-article","created":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T06:14:41Z","timestamp":1651040081000},"page":"1577-1582","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Marked safety and high diagnostic yield of freehand ultrasound\u2010guided core\u2010needle biopsies performed by pulmonologists"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6994-4451","authenticated-orcid":false,"given":"Evgeni","family":"Gershman","sequence":"first","affiliation":[{"name":"Pulmonary Division Rabin Medical Center  Petah Tikva Israel"},{"name":"Sackler Faculty of Medicine Tel Aviv University  Tel Aviv 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