{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:30:33Z","timestamp":1747182633914,"version":"3.40.5"},"reference-count":8,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2022,5,20]],"date-time":"2022-05-20T00:00:00Z","timestamp":1653004800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Docetaxel is a cytotoxic taxane frequently used to treat patients with various cancers, including non\u2010small cell lung cancer (NSCLC). Docetaxel is known to cause acute myalgias, arthralgias, and neuropathy, but there have been few published case reports of myositis. Here, we describe a rare case of docetaxel\u2010induced myositis diagnosed based on laboratory data, thigh magnetic resonance imaging (MRI), and electromyography (EEG). A 66\u2010year\u2010old male was admitted for thigh pain and fatigue that onset 1\u00a0week prior. He had been diagnosed with stage IVA (cT4N0M1a) NSCLC 3\u2009years ago and had been started on docetaxel (60\u2009mg\/m<jats:sup>2<\/jats:sup> intravenously every 3\u2009weeks; fourth\u2010line chemotherapy) 1\u00a0month earlier. After the second cycle, he developed both thigh pain and fatigue. On admission, his creatinine phosphokinase (CPK) level was elevated, thigh MRI revealed diffuse muscle edema, and EEG showed myogenic changes. We found no plausible cause for myositis except docetaxel. He was diagnosed with myositis and treated with oral prednisolone. His symptoms were relieved and the CPK level declined. Although rare, this case indicates that clinicians should consider the possibility of myositis as a complication in patients on docetaxel.<\/jats:p>","DOI":"10.1111\/1759-7714.14480","type":"journal-article","created":{"date-parts":[[2022,5,21]],"date-time":"2022-05-21T01:00:10Z","timestamp":1653094810000},"page":"2075-2077","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A rare case of docetaxel\u2010induced myositis in a patient with a lung adenocarcinoma"],"prefix":"10.1111","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9775-229X","authenticated-orcid":false,"given":"Akane","family":"Ishida","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayumi","family":"Ushio","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masao","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Ishii","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Go","family":"Naka","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoyasu","family":"Iikura","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinyu","family":"Izumi","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayuki","family":"Hojo","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruhito","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine National Center for Global Health and Medicine  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,20]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"8","article-title":"A case of docetaxel induced myositis and review of the literature","volume":"795242","author":"Perel\u2010Winkler A","year":"2015","journal-title":"Case Rep Rheumatol"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002281-199411000-00007"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-011-0169-7"},{"key":"e_1_2_5_5_1","first-page":"523","article-title":"Acute myopathy in a patient with lung adenocacrinoma treated with gemcitabine and docetaxel","volume":"25","author":"Ardavanis AS","year":"2005","journal-title":"Anticancer Res"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2005.00846.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1482.144361"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/CAD.0000000000000620"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijnm.IJNM_25_20"}],"container-title":["Thoracic Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.14480","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/1759-7714.14480","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/1759-7714.14480","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T03:51:38Z","timestamp":1692849098000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/1759-7714.14480"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,20]]},"references-count":8,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2022,7]]}},"alternative-id":["10.1111\/1759-7714.14480"],"URL":"https:\/\/doi.org\/10.1111\/1759-7714.14480","archive":["Portico"],"relation":{},"ISSN":["1759-7706","1759-7714"],"issn-type":[{"type":"print","value":"1759-7706"},{"type":"electronic","value":"1759-7714"}],"subject":[],"published":{"date-parts":[[2022,5,20]]},"assertion":[{"value":"2022-04-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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