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Based on the relationship between the tumor and the interlobar fissure, tumors can be categorized into close to the fissure, causing the fissure, and involving the fissure. The complete ablation rate, local progression\u2010free survival, complications, and associated factors were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All 66 histologically proven tumors were treated using computed tomography\u2010guided microwave ablation. The complete ablation rate was 95.5%. Local progression\u2010free survival at 3, 6, 9, and 12\u2009months were 89.4%, 83.3%, 74.2%, and 63.6%, respectively. The complications included pneumothorax (34.8%), pleural effusion (24.2%), cavity (18.2%), and pulmonary infection (7.6%). There were statistical differences in the incidence of pneumothorax, cavity, and delayed complications between the groups with and without antenna punctures through the fissure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Microwave ablation is a safe and effective treatment for lung tumor adjacent to the interlobar fissure. Antenna puncturing though the interlobar fissure may be a potential risk factor for pneumothorax, cavity, and delayed complications.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.14589","type":"journal-article","created":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T07:05:30Z","timestamp":1659337530000},"page":"2557-2565","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Safety and efficacy of microwave ablation for lung cancer adjacent to the interlobar fissure"],"prefix":"10.1111","volume":"13","author":[{"given":"Nan","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine Shandong Lung Cancer Institute  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingwen","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital Shandong Medicine and Health Key Laboratory of Cardiac Electrophysiology and Arrhythmia  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine Shandong Lung Cancer Institute  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoliang","family":"Xue","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine Shandong Lung Cancer Institute  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhichao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine Shandong Lung Cancer Institute  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pikun","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Oncology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine Shandong Lung Cancer Institute  Jinan 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