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In the present case, we performed three pleural fluid investigations, including transbronchial biopsy of the primary tumor, transesophageal endoscopic ultrasound\u2010guided fine needle aspiration (EUS\u2010FNA) of lymph node metastasis, and thoracoscopic biopsy of the pleural seeding sites. Among the three investigations, thoracoscopic biopsy alone successfully obtained a sufficient amount of tissue. Thus, it is important to determine the technique and site of biopsy, as multiple biopsies are not only burdensome to the patient, but also lead to significant delays in therapy induction.<\/jats:p>","DOI":"10.1111\/1759-7714.14738","type":"journal-article","created":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T04:50:15Z","timestamp":1669006215000},"page":"85-88","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: A case report"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5241-3486","authenticated-orcid":false,"given":"Kei","family":"Kunimasa","sequence":"first","affiliation":[{"name":"Department of Thoracic Oncology Osaka International Cancer Institute  Osaka 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