{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:31:26Z","timestamp":1747182686342,"version":"3.40.5"},"reference-count":24,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T00:00:00Z","timestamp":1678665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To investigate the effect of continuous oral aspirin in perioperative period on bleeding in pneumonectomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 170 patients who underwent pneumonectomy in our hospital from March 2021 to March 2022 were selected as the study objects. All patients took oral aspirin before surgery and did not take other antiplatelet agent or anticoagulants at the same time. The continuation group included 85 cases and continued to take aspirin 100\u2009mg\/day during the perioperative period, and the interruption group included 85 cases who stopped aspirin for 7\u2009days before surgery and 3\u2009days after surgery, without bridging therapy. The intraoperative blood loss, operation time, conversion to thoracotomy rate, postoperative bleeding rate, blood transfusion rate, thrombotic events, postoperative drainage volume, length of hospital stay, and total hospital cost of the two groups were compared.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no statistically significant differences in intraoperative blood loss, operative time, rate of conversion to open, postoperative drainage, hospital stay, and cost between the two groups (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05), and there were no reoperations due to bleeding between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Aspirin should be continued throughout the perioperative period in all high\u2010risk patients requiring pneumonectomy after balancing ischemic\u2010bleeding risks.<\/jats:p><\/jats:sec>","DOI":"10.1111\/1759-7714.14846","type":"journal-article","created":{"date-parts":[[2023,3,14]],"date-time":"2023-03-14T06:04:40Z","timestamp":1678773880000},"page":"1071-1076","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of perioperative aspirin continuation on bleeding after pneumonectomy"],"prefix":"10.1111","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6674-7559","authenticated-orcid":false,"given":"Qirui","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yili","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinbai","family":"Miao","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengcai","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, Beijing Institute of Respiratory Medicine and Beijing Chao\u2010Yang Hospital Capital Medical University  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,3,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx419"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocpiqo.2022.09.006"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.13593"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2022.07.025"},{"issue":"6","key":"e_1_2_7_6_1","first-page":"639","article-title":"Shanghai Medical Association; 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