{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:31:28Z","timestamp":1747182688020,"version":"3.40.5"},"reference-count":16,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2023,3,28]],"date-time":"2023-03-28T00:00:00Z","timestamp":1679961600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Thoracic Cancer"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Primary tracheal small\u2010cell carcinoma is rare, and is often treated using small\u2010cell lung cancer guidelines given that no standard treatment has been established for it. We report a patient in whom nodules appeared in the trachea and left main bronchus 11\u2009months after surgery for pulmonary large\u2010cell neuroendocrine carcinoma; a biopsy revealed small\u2010cell carcinoma. Given the absence of malignant lesions elsewhere in the body, the lesions were diagnosed as primary tracheal small\u2010cell carcinoma. Respiratory failure progressed rapidly owing to airway stenosis caused by the growing lesion, and the patient required nasal high\u2010flow therapy. However, the lesions shrank a few days after commencing first\u2010line chemotherapy, and his respiratory failure resolved. Accelerated hyperfractionated radiotherapy was administered in conjunction with the third course of chemotherapy, and the patient ultimately achieved a complete response. Although the lesions were initially suspected of being postoperative recurrence of pulmonary large\u2010cell neuroendocrine carcinoma, the fact that the biopsy revealed them to be primary tracheal small\u2010cell carcinoma indicates that intra\u2010airway nodules that appear after lung cancer surgery may possibly be primary tracheal tumors.<\/jats:p>","DOI":"10.1111\/1759-7714.14860","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T01:00:38Z","timestamp":1680051638000},"page":"1212-1216","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Primary tracheal small\u2010cell carcinoma detected 11\u2009months after surgery for pulmonary large\u2010cell neuroendocrine carcinoma: A case report"],"prefix":"10.1111","volume":"14","author":[{"given":"Chihiro","family":"Sugimoto","sequence":"first","affiliation":[{"name":"Respiratory Disease Center Yokohama City University Medical Center  4\u201057 Urafune\u2010cho, Minami\u2010ku Yokohama 232\u20100024 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2365-144X","authenticated-orcid":false,"given":"Shuhei","family":"Teranishi","sequence":"additional","affiliation":[{"name":"Respiratory Disease Center Yokohama City University Medical Center  4\u201057 Urafune\u2010cho, Minami\u2010ku Yokohama 232\u20100024 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoe","family":"Sawazumi","sequence":"additional","affiliation":[{"name":"Division of Pathology Yokohama City University Medical Center  4\u201057 Urafune\u2010cho, Minami\u2010ku Yokohama 232\u20100024 Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Nagaoka","sequence":"additional","affiliation":[{"name":"Respiratory Disease Center Yokohama City University Medical Center  4\u201057 Urafune\u2010cho, Minami\u2010ku Yokohama 232\u20100024 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